Results 241 to 250 of about 447,090 (290)

Aging‐Driven Blood–Brain Barrier Dysfunction and Its Impact on CNS Cancer Susceptibility: A Comprehensive Narrative Review

Aging and Cancer, EarlyView.
Aging weakens the blood–brain barrier (BBB), increasing susceptibility to CNS cancers and complicating treatment. This review examines BBB deterioration, its impact on drug delivery, and potential interventions like targeting neuroinflammation and advanced therapies.
Quang La, Aiman Baloch, David F. Lo
wiley   +1 more source

The Impact of the Tumor Microenvironment on the Effect of IL-1β Blockade in NSCLC: Biomarker Analyses from CANOPY-1 and CANOPY-N Trials. [PDF]

Cancer Res Commun
Solomon BJ, Tan DSW, de Castro G, Cobo M, Garassino MC, Zhang J, Johnson BE, Lee JM, Garrido P, Butler AA, Pelletier MR, Savchenko A, Ji L, Brase JC, Caparica R, Demanse D, Wu J, Bossen C, Mok T.   +18 more
europepmc   +1 more source

Injection of ROS-Responsive Hydrogel Loaded with IL-1β-targeted nanobody for ameliorating myocardial infarction. [PDF]

Bioact Mater
Wang L, Yu C, You T, Zhang X, Su H, Cao B, Anwaier S, Xiang H, Dai C, Long X, Han L, Zhang D, Wang J, Zhu P, Yan X, Liang J, Chen Z, Huang H, Zhu S, Sun T, Chen J, Zhu P.   +21 more
europepmc   +1 more source

Caspase-1 Variants and Plasma IL-1β in Patients with Leishmania guyanensis Cutaneous Leishmaniasis in the Amazonas. [PDF]

Int J Mol Sci
de Souza JL, de Farias Guerra MV, de Mesquita TGR, Junior JDES, Sequera HDG, da Silva LS, da Silva LA, Moura FM, Menescal LSF, da Costa Torres J, Pinheiro SK, Kerr HKA, Ogusku MM, de Souza MLG, de Moura Neto JP, Sadahiro A, Ramasawmy R.   +16 more
europepmc   +1 more source

Cyclic Tensile Strain Acts as an Antagonist of IL-1β Actions in Chondrocytes

, 2000
Zhongfa Xu, Michael Buckley, Christopher H. Evans, Sudha Agarwal   +3 more
openalex   +1 more source

IL-1β in Neoplastic Disease and the Role of Its Tumor-Derived Form in the Progression and Treatment of Metastatic Prostate Cancer. [PDF]

Cancers (Basel)
Oyende Y, Taus LJ, Fatatis A.
europepmc   +1 more source

From 2D to 3D gamma passing rate tolerance and action limits for patient‐specific quality assurance in volumetric‐modulated arc therapy

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Background Volumetric modulated arc therapy (VMAT) requires an accurate patient‐specific quality assurance (PSQA) program. In clinical practice, this is usually performed using the γ‐index and the two‐dimensional gamma passing rate (2D %GP). A three‐dimensional (3D) index incorporating the patient anatomy could be more useful for the 3D dose ...
Christos Zarros, George Patatoukas, Nikos Kollaros, Marina Chalkia, Andromachi Kougioumtzopoulou, Vasilios Kouloulias, Kalliopi Platoni   +6 more
wiley   +1 more source

IL-1β enhances susceptibility to atrial fibrillation in mice by acting through resident macrophages and promoting caspase-1 expression. [PDF]

Nat Cardiovasc Res
Moreno-Loaiza O, Soares VC, de Assumpção Souza M, Vera-Nuñez N, Rodriguez de Yurre Guirao A, da Silva TP, Pozes AB, Perticarrari L, Monteiro E, Albino MC, Silva SB, Dias SSG, Maciel L, Muzi-Filho H, de Oliveira DF, Braga BC, Diniz LP, Cruz MC, Barbosa SR, Castro-Junior AB, Conde L, Cabral-Castro MJ, de Souza OF, Tavares Pinheiro MV, Araújo de Oliveira Junior N, Rezende de Siqueira L, Cosenza RP, Munhoz da Fontoura C, Secco JCP, da Rocha Ferreira J, Silvestre de Sousa A, Albuquerque D, Luiz RR, Nicolau-Neto P, Pretti MA, Boroni M, Bonamino MH, Kasai-Brunswick TH, Mello DB, Gonçalves-Silva T, Ramos IP, Bozza FA, Madeiro JPDV, Pedrosa RC, Carneiro-Ramos MS, da Silva Martinho H, Bozza PT, Mesquita de Souza F, Victor Lucena da Silva G, Cunha TM, Uzelac I, Fenton F, Moll-Bernardes R, Paiva CN, Escobar AL, Medei E.   +55 more
europepmc   +1 more source

Inflammatory Activation of Human Brain Endothelial Cells by Hypoxic Astrocytes In Vitro is Mediated by IL-1β

, 2000
Wandong Zhang, Catherine Delano Smith, Clare Howlett, Danica Stanimirovic   +3 more
openalex   +1 more source

Evaluation of the effect of metal stents on dose perturbation in the carbon beam irradiation field

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Propose Carbon ion therapy is indicated for cases in which stents have been inserted, such as bile ducts, but the effect of metal stents on carbon ion therapy is unclear. In this study, the dose perturbation of carbon ion therapy caused by metallic bile duct stents was evaluated by dosimetry. Materials and methods Five different types of metal
Yuya Miyasaka, Tetsuya Ishizawa, Yoshihito Nawa, Hikaru Souda, Shohei Kawashiro, Hongbo Chai, Miyu Ishizawa, Hiraku Sato, Takeo Iwai   +8 more
wiley   +1 more source