Results 271 to 280 of about 447,090 (290)

Primed Mesenchymal Stem Cells by IFN-γ and IL-1β Ameliorate Acute Respiratory Distress Syndrome through Enhancing Homing Effect and Immunomodulation. [PDF]

Biomol Ther (Seoul)
Kong T, Seo SK, Han YS, Seo WM, Kim B, Kim J, Cho YJ, Lee S, Kang KS.   +8 more
europepmc   +1 more source

Explorative Study of Modulatory Effects of Notochordal Cell-Derived Extracellular Vesicles on the IL-1β-Induced Catabolic Cascade in Nucleus Pulposus Cell Pellets and Explants. [PDF]

JOR Spine
van Maanen JC, Bach FC, Snuggs JW, Ito K, Wauben MHM, Le Maitre CL, Tryfonidou MA.   +6 more
europepmc   +1 more source

Systematic Review on the Role of IL-6 and IL-1β in Cardiovascular Diseases. [PDF]

J Cardiovasc Dev Dis
Katkenov N, Mukhatayev Z, Kozhakhmetov S, Sailybayeva A, Bekbossynova M, Kushugulova A.   +5 more
europepmc   +1 more source

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Myricitrin regulates proliferation, apoptosis and inflammation of chondrocytes treated with IL-1β

Cellular and Molecular Biology, 2020
Osteoarthritis (OA) is a clinical disease which seriously affects the quality of life of sufferers. Although the pathogenesis of OA has not been fully unraveled, it is may be due to increased levels of pro-inflammatory cytokines, activation of inflammation-related signaling pathways, and degradation of extracellular matrix.
Jian-Bo Xue, Ying-Ling Zhou, Tao Sun, Xiao-Feng Wang   +3 more
openaire   +3 more sources

Effects of UVA on TNF-α, IL-1β, and IL-10 expression levels in human keratinocytes and intervention studies with an antioxidant and a JNK inhibitor

Photodermatology, Photoimmunology & Photomedicine, 2010
To understand the expressions and transduction pathways of cytokines in ultraviolet (UV)A-irradiated keratinocytes.We cultured human keratinocytes of the HaCaT cell line and investigated both mRNA and protein expressions of cytokines in cells that were not irradiated or were exposed to 2.4 J/cm(2) UVA, with or without an antioxidant (beta-carotene) or ...
Guo-Qing Dong, Ying Zhang, Liwen Hu, Jing-Hai Li, Yang Liu, Qian Gao, Li An   +6 more
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Regulation of HAS expression in human synovial lining cells of TMJ by IL-1β

Archives of Oral Biology, 2008
Hyaluronan (HA), a major glycosaminoglycan of synovial fluid, is synthesised by a class of membrane-bound HA synthase (HAS) proteins. In the present study, we investigated the regulatory roles of IL-1beta on HAS gene expression and HA production by the fibroblastic synovial lining cells.
Xing Long, Xing Long, Jacinta M. Doocey, Winson C.C. Lee, Jin Ke, Jin Ke, Fan Zhu, Jian Li, Jian Li, Qinggong Meng, Qinggong Meng   +10 more
openaire   +4 more sources

IL-4 and IL-10 modulation of CD40-mediated signaling of monocyte IL-1beta synthesis and rescue from apoptosis.

The Journal of Immunology, 1997
Abstract Previous studies have demonstrated that the interaction of CD40 on monocytes with CD40 ligand, present on activated CD4+ T cells, induces monocyte inflammatory cytokine synthesis and rescues monocytes from apoptosis. These findings suggest a role for CD40 signaling of monocyte activation in the maintenance and/or exacerbation of
Poe, Jonathan C., Wagner, David H., Miller, Robert W., Stout, Robert D., Suttles, Jill   +4 more
openaire   +2 more sources

GM-CSF Induction in Human Lung Fibroblasts by IL-1β, TNF-α, and Macrophage Contact

Journal of Interferon & Cytokine Research, 2003
Fibroblast-derived cytokines may play crucial roles in airway inflammation. In this study, we analyzed expression of the inflammatory cytokine, granulocyte-macrophage colony-stimulating factor (GM-CSF), a major eosinophilopoietin, by normal human lung fibroblast (NHLF) cells and its regulation by monokines and macrophage contact.
Fitzgerald, S. Matthew, Chi, David S., Hall, H. Kenton, Reynolds, Scott A., Aramide, Omolola, Lee, Steven A., Krishnaswamy, Guha   +6 more
openaire   +4 more sources

Suppression of IL-1β promotes beneficial accumulation of fibroblast-like cells in atherosclerotic plaques in clonal hematopoiesis

Nature Cardiovascular Research
Clonal hematopoiesis (CH) is an independent risk factor for atherosclerotic cardiovascular disease. Murine models of CH suggest a central role of inflammasomes and IL-1β in accelerated atherosclerosis and plaque destabilization. Here we show using single-cell RNA sequencing in human carotid plaques that inflammasome components are enriched in ...
Trevor P. Fidler, Andrew Dunbar, Eunyoung Kim, Brian Hardaway, Jessica Pauli, Chenyi Xue, Sandra Abramowicz, Tong Xiao, Kavi O’Connor, Nadja Sachs, Nan Wang, Lars Maegdefessel, Ross Levine, Muredach Reilly, Alan R. Tall   +14 more
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The Effect of Obesity on IL-1β, IL-1Ra, and Leptin Following Acute Mental Stress

2014
VCU Theses and ...
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