Results 271 to 280 of about 2,610,317 (379)

Restoration of vascular dysfunction resulting from maternal high-fat diet via modulation of the NLRP3/IL-1β axis

Yuxuan Xiao, Xiaoning Bi, Rongjie Zhang, Yu Li, Wei Sun, Yingxue Hao   +5 more
openalex   +1 more source

Understanding the mechanism of IL-1β secretion

Cytokine & growth factor reviews, 2011
G. López-Castejón, D. Brough
semanticscholar   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Comparative Transcriptomic Profiling Identifies IL-1β as a Non-Canonical Driver of Human Dendritic Cell Maturation. [PDF]

Iran J Biotechnol
Yilmaz V.
europepmc   +1 more source

Induction of antimicrobial peptides secretion by IL-1β enhances human amniotic membrane for regenerative medicine [PDF]

, 2017
Fatemeh A. Tehrani, Khashayar Modaresifar, Sara Azizian, Hassan Niknejad   +3 more
openalex   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

MSC-EVs alleviate osteoarthritic joint pain and degeneration by suppressing IL-1β/NGF signaling. [PDF]

Genes Dis
Teo KYW, Wen C, Wong RCW, Toh WS.
europepmc   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source

Cytochrome b5 reductase orchestrates IL-1β production in macrophages through FAD. [PDF]

Cell Death Dis
Fu J, Liu Z, Zhang H, Zhang X, Liu S, Mei X, Zeng X, Ren W.   +7 more
europepmc   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source