Results 351 to 360 of about 2,610,317 (379)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Analysis of IL-6 and IL-1β Gene coding and study on specific clearance using histidine-grafted PVDF membranes. [PDF]

Glob Med Genet
Li K, Liu J, Zhang K, Liu H, Yang Y, Na R, Ma H, Cui X.   +7 more
europepmc   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Taurine Attenuates M1 Macrophage Polarization and IL-1β Production by Suppressing the JAK1/2-STAT1 Pathway via Metabolic Reprogramming. [PDF]

Biology (Basel)
Zhang Z, Li D, He S, Xu W, Lv Q, Wang Y, Xu J, Yu Z, Liu S, Ge Y, Shi F, Yan Y.   +11 more
europepmc   +1 more source

FABP5 in skin macrophages mediates saturated fat-induced IL-1β signaling in psoriatic inflammation. [PDF]

Cell Rep
Yu J, Hao J, Yorek MS, Jiang X, Avellino A, Liu S, Han X, Shilyansky J, Wang Z, Wang Y, Kang Z, Jabbari A, Li B.   +12 more
europepmc   +1 more source

Modulation of IL-1β and TGF-β1 Gene Expression in Stress-Induced Depression Rat Supplemented with Malaysian Acacia Honey. [PDF]

Foods
Mohamed AS, Muhammad H, Nik Zainuddin NAS, Md Nasir NL, Abd Rahman MRA, Siu LM, Md Akim A, Ramasamy K, Hazizul Hasan M, Eshak Z.   +9 more
europepmc   +1 more source

[Retracted] Isorhamnetin inhibits IL‑1β‑induced expression of inflammatory mediators in human chondrocytes. [PDF]

Mol Med Rep
Li J, Wu R, Qin X, Liu D, Lin F, Feng Q.
europepmc   +1 more source

Molecular Characterization, Expression Responses and Antipathogenic Bacterial Function of Interleukin-1β (IL-1β) in Asian Seabass (<i>Lates calcarifer</i> Bloch, 1790). [PDF]

Biomolecules
Srisapoome P, Muangrerk C, Uchuwittayakul A, Wongpanya R.   +3 more
europepmc   +1 more source

ARA290 Attenuates Apical Periodontitis via SIRT1/NF-κB/IL-1β Pathway Modulation

Yuting Wang, Yifei Tang, Mingfei Wang, Wenlan Li, Wenli Mu, Abdelrahman Seyam, Yiping Dai, Tiezhou Hou, Xiaoyue Guan   +8 more
openalex   +1 more source

LINC01198 activates Hippo signaling to stimulate IL-1β autocrine for driving vemurafenib resistance by associating with TAOK1/2 in melanoma. [PDF]

Cell Death Discov
Liu J, Liang X, Wang K, Zhang C, Li C, Zhao L, Kuang Y, Wang M, Liu J, Zhou L, Ma L.   +10 more
europepmc   +1 more source