Results 361 to 370 of about 2,610,317 (379)

Myricitrin regulates proliferation, apoptosis and inflammation of chondrocytes treated with IL-1β

Cellular and Molecular Biology, 2020
Osteoarthritis (OA) is a clinical disease which seriously affects the quality of life of sufferers. Although the pathogenesis of OA has not been fully unraveled, it is may be due to increased levels of pro-inflammatory cytokines, activation of inflammation-related signaling pathways, and degradation of extracellular matrix.
Tao, Sun, Jian-Bo, Xue, Ying-Ling, Zhou, Xiao-Feng, Wang   +3 more
openaire   +2 more sources

NLRP3 inflammasome mediates M1 macrophage polarization and IL-1β production in inflammatory root resorption.

Journal of Clinical Periodontology, 2020
AIMS To explore the involvement of NOD-like receptor protein 3 (NLRP3) inflammasome and M1 macrophage in root resorption (RR). METHODS A rat RR model was established by excessive orthodontic force.
Jie Zhang, Xinqiang Liu, Chunyan Wan, Yang Liu, Yaqi Wang, Chenda Meng, Yipeng Zhang, Chunmiao Jiang   +7 more
semanticscholar   +1 more source

Throwing IL-1β for a loop.

Science immunology
The lncRNA AMANZI exerts cis-regulatory control of IL-1β-mediated inflammation.
Noah Jacobs, Gabriel K. Griffin
semanticscholar   +1 more source

Effects of UVA on TNF-α, IL-1β, and IL-10 expression levels in human keratinocytes and intervention studies with an antioxidant and a JNK inhibitor

Photodermatology, Photoimmunology & Photomedicine, 2010
To understand the expressions and transduction pathways of cytokines in ultraviolet (UV)A-irradiated keratinocytes.We cultured human keratinocytes of the HaCaT cell line and investigated both mRNA and protein expressions of cytokines in cells that were not irradiated or were exposed to 2.4 J/cm(2) UVA, with or without an antioxidant (beta-carotene) or ...
Li, An, Guo-Qing, Dong, Qian, Gao, Ying, Zhang, Li-Wen, Hu, Jing-Hai, Li, Yang, Liu   +6 more
openaire   +2 more sources

IL-1β^+ macrophages fuel pathogenic inflammation in pancreatic cancer

Nature, 2023
N. Caronni, Federica La Terza, F. M. Vittoria, G. Barbiera, Luca Mezzanzanica, Vincenzo Cuzzola, Simona Barresi, Marta Pellegatta, P. Canevazzi, Garett Dunsmore, Carlo Leonardi, Elisa Montaldo, Eleonora Lusito, E. Dugnani, A. Citro, M. Ng, M. Schiavo Lena, Denise Drago, A. Andolfo, Silvia Brugiapaglia, A. Scagliotti, A. Mortellaro, V. Corbo, Zhaoyuan Liu, A. Mondino, P. Dellabona, L. Piemonti, C. Taveggia, Claudio Doglioni, P. Cappello, Francesco Novelli, M. Iannacone, L. Ng, F. Ginhoux, S. Crippa, Massimo Falconi, Chiara Bonini, L. Naldini, M. Genua, R. Ostuni   +39 more
semanticscholar   +1 more source

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors

Nature Medicine, 2009
F. Ghiringhelli, L. Apetoh, A. Tesnière, L. Aymeric, Yuting Ma, Carla Ortiz, K. Vermaelen, T. Panaretakis, G. Mignot, E. Ullrich, J. Perfettini, F. Schlemmer, E. Tasdemir, M. Uhl, P. Génin, A. Civas, B. Ryffel, J. Kanellopoulos, J. Tschopp, F. André, R. Lidereau, N. McLaughlin, N. Haynes, M. Smyth, G. Kroemer, L. Zitvogel   +25 more
semanticscholar   +1 more source

Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production

Nature, 2008
T. Saitoh, Naonobu Fujita, M. Jang, S. Uematsu, Bo-Gie Yang, T. Satoh, Hiroko Omori, Takeshi Noda, N. Yamamoto, M. Komatsu, Keiji Tanaka, T. Kawai, T. Tsujimura, O. Takeuchi, T. Yoshimori, S. Akira   +15 more
semanticscholar   +1 more source

Neonatal Colonic Inflammation Sensitizes the Colon Epithelium for Exacerbated IL-1Î' Activation when Subjected to a Second Insult in Adult-Life

Gastroenterology, 2017
Xiaoying S. Zhong, Qingjie Li
openaire   +1 more source

Human T cell activation by APC: Synergistic effect of accessory signaling by CD40, IL-1β and IL-12

Immunology Letters, 1997
openaire   +1 more source