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Extracellular Vesicles From Schistosoma mansoni Adult Worms Stimulate IL-10 Release by B Cells. [PDF]
Parasite ImmunolKuipers ME +9 more
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IL‐10 and IL‐10 receptor defects in humans
Annals of the New York Academy of Sciences, 2011Inflammatory bowel disease (IBD), which includes Crohn's disease (CD) and ulcerative colitis (UC), is chronic in nature and is characterized by abdominal pain, diarrhea, bleeding, and malabsorption. It is considered a complex multigenic and multifactorial disorder that results from disturbed interactions between the immune system and commensal bacteria
Erik-Oliver, Glocker +4 more
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IL-10 in Humans: Lessons from the Gut, IL-10/IL-10 Receptor Deficiencies, and IL-10 Polymorphisms
2014Inflammatory bowel disease (IBD) represents a heterogeneous group of gastrointestinal disorders, where commensal gut flora provokes an either (a) insufficient or (b) uncontrolled immune response. This results either in a lack of or in excessive inflammation mainly manifesting as Crohn's disease or ulcerative colitis.
Engelhardt, Karin R., Grimbacher, Bodo
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Title: IL-10-producing T cells and their dual functions.
Seminars in Immunology, 2019Interleukin (IL)-10 is considered a prototypical anti-inflammatory cytokine, which significantly contributes to the maintenance and reestablishment of immune homeostasis. However, this classical view fails to fully describe the pleiotropic roles of IL-10.
T. Bedke +4 more
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Leukemia & Lymphoma, 2002
In addition to interleukin (IL)-6, IL-10 is considered as one of the most important cytokines regulating the proliferation and cellular characteristics of myeloma cells. It is still unclear from the clinical data how serum IL-10 levels of various stages of myeloma, are related to clinical manifestations of this disease.
Takemi, Otsuki +7 more
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In addition to interleukin (IL)-6, IL-10 is considered as one of the most important cytokines regulating the proliferation and cellular characteristics of myeloma cells. It is still unclear from the clinical data how serum IL-10 levels of various stages of myeloma, are related to clinical manifestations of this disease.
Takemi, Otsuki +7 more
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IL-10 or not IL-10: that is the question
Nature Immunology, 2007Four new papers focused on how interleukin 10–producing cells are induced have led to some unexpected and intriguing observations on the nature of interleukin 17–producing T helper cells.
Dragana Jankovic, Giorgio Trinchieri
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1995
In the 5 years since its discovery, the pleiotropic cytokine IL-10 has been shown to play an important role in the regulation of lymphoid and myeloid cells. IL-10 was detected independently in several laboratories. Fiorentino et al. [1] described a cytokine secreted by ‘type 2’ murine helper T-cell clones which inhibited cytokine production by ‘type 1’
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In the 5 years since its discovery, the pleiotropic cytokine IL-10 has been shown to play an important role in the regulation of lymphoid and myeloid cells. IL-10 was detected independently in several laboratories. Fiorentino et al. [1] described a cytokine secreted by ‘type 2’ murine helper T-cell clones which inhibited cytokine production by ‘type 1’
openaire +3 more sources