Results 81 to 90 of about 15,170,590 (380)

Unheard and Under‐Supported: Health‐Related Quality of Life in Children, Adolescents, and Young Adults With Sickle Cell Disease

open access: yesPediatric Blood &Cancer, EarlyView.
Abstract Background Sickle cell disease (SCD) is an autosomal recessive hemoglobinopathy affecting millions of individuals worldwide. The clinical expression and psychosocial burden of SCD vary widely across geographical, cultural, and healthcare system contexts, underscoring the need for setting‐specific approaches to assessment.
Desiré Fantasia   +7 more
wiley   +1 more source

The evolving landscape of IL-10, IL-22 and IL-26 in pleurisy especially in tuberculous pleurisy

open access: yesRespiratory Research
Pleurisy can be categorized as primary or secondary, arising from immunological, tumorous, or microbial conditions. It often results in lung structure damage and the development of various respiratory issues.
Qian Niu, Meng Wang, Xian-Sheng Liu
doaj   +1 more source

IL-10 and pregnancy complications

open access: yesClinical and Experimental Obstetrics & Gynecology, 2017
Successful pregnancy depends on the ability of the mother's immune system to undergo a process of immunoregulation in order to tolerate the fetus, and also to create and sustain a nurturing environment during all the stages of pregnancy. Several reports point to interleukin 10 (IL-10) as being vital for normal pregnancy, and low IL-10 levels as being ...
F Y, Azizieh, R, Raghupathy
openaire   +2 more sources

IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells.

open access: yesJournal of Immunology, 1991
Murine IL-10 (cytokine synthesis inhibitory factor) inhibits cytokine production by Th1 cell clones when they are activated under conditions requiring the presence of APC. By preincubating APC with IL-10, we demonstrate that IL-10 acts principally on APC
D. Fiorentino   +6 more
semanticscholar   +1 more source

Imaging of High‐Risk Neuroblastoma: Recommendations From SIOPEN Radiology and Nuclear Medicine Specialty Committees

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Neuroblastoma is the most common extracranial solid tumor in early childhood. Its clinical behavior is highly variable, ranging from spontaneous regression to fatal outcome despite intensive treatment. The International Society of Pediatric Oncology Europe Neuroblastoma Group (SIOPEN) Radiology and Nuclear Medicine Specialty Committees ...
Annemieke Littooij   +11 more
wiley   +1 more source

结直肠癌患者血清IL-23和IL-10水平的检测及其意义

open access: yesZhongguo shiyan zhenduanxue, 2011
目的探讨结直肠癌进展过程中,患者血清中几种细胞因子水平的变化及其在肿瘤进程中的意义。方法纳入50例患者及20例健康志愿者,运用ELISA方法检测各组血清IL-23I、L-17I、L-10和IFN-α水平的变化。结果结直肠癌患者血清IL-23和IL-10水平显著高于对照组,而且Ⅳ期患者血清IL-10水平显著高于Ⅰ、Ⅱ、Ⅲ期。结论与IL-17和IFN-α相比,患者血清中IL-23和IL-10表达水平显著增加;此外,患者血清中IL-10的高水平表达可能促进了结直肠癌的发展。
吕坤, 张莺莺
doaj  

CHARACTERISTICS OF LOCAL INFLAMMATION IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE: DEPENDENCE ON SEVERITY STAGE

open access: yesМедицинская иммунология, 2014
A group of 112 patients with chronic obstructive pulmonary disease of severity were included into the study. Differential cell counts, IL-8, TNFα, and IL-10 concentrations were assayed in sputum and bronchial lavage.
L. Yu. Dolinina   +4 more
doaj   +1 more source

Study on relationship between elderly sarcopenia and inflammatory cytokine IL-6, anti-inflammatory cytokine IL-10

open access: yesBMC Geriatrics, 2018
Background and objectivesThe pathophysiological mechanism of sarcopenia in the elderly has not yet been fully understood. Here, we aim to explore the relationship between sarcopenia and the inflammatory cytokine interleukin-6 (IL-6), and the anti ...
Yu Rong   +4 more
semanticscholar   +1 more source

Effects of Cancer Treatment on Somatosensory and Nociceptive Processing in Children and Adolescents: A Systematic Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Chemotherapy‐induced peripheral neuropathy remains a major complication in pediatric cancer, with disrupted somatosensory and nociceptive processing being a key aspect. This review synthesizes empirical studies on alterations in somatosensory and nociceptive processing in children and adolescents with cancer.
Julia Schweiger   +4 more
wiley   +1 more source

Computer-aided designing of immunosuppressive peptides based on IL-10 inducing potential

open access: yesScientific Reports, 2017
In the past, numerous methods have been developed to predict MHC class II binders or T-helper epitopes for designing the epitope-based vaccines against pathogens.
Gandharva Nagpal   +6 more
semanticscholar   +1 more source

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