Results 121 to 130 of about 20,539 (229)

Endotypes and Phenotypes in ILD: Is It Time to Reclassify ILD by Risk Stratification?

Biomedicines
Interstitial lung diseases (ILD) comprise a heterogeneous group of disorders that present significant challenges in both diagnosis and management due to their varied nature, which encompasses different degrees of inflammation and fibrosis affecting lung tissue [...]
Francesco Amati, Anna Stainer, Stefano Aliberti   +2 more
openaire   +3 more sources

Perioperative Durvalumab for Resectable NSCLC: Updated Outcomes for Japanese Patients in AEGEAN

Cancer Science, EarlyView.
In prespecified exploratory analyses of Japanese patients with resectable NSCLC enrolled in the AEGEAN trial, perioperative durvalumab plus neoadjuvant chemotherapy demonstrated clinically meaningful improvements in the primary endpoints of EFS and pCR versus neoadjuvant chemotherapy alone.
Tetsuya Mitsudomi, John V. Heymach, Yoshitsugu Horio, Fumihiro Tanaka, Hiroshi Tanaka, Shoichi Kuyama, Morihito Okada, Shinichi Toyooka, Yasutaka Watanabe, Martin Reck, David Harpole, Janis M. Taube, Yuka Olivo, Huiling Xiong, Tamer M. Fouad, Allen Chen, Hiroaki Akamatsu   +16 more
wiley   +1 more source

Yagya Therapy as a Supportive Integrative Intervention in Interstitial Lung Disease (ILD): A Comprehensive Scientific Review [PDF]

Interstitial lung disease (ILD) encompasses a group of pulmonary disorders characterized by inflammation and scarring of the lung tissues. Despite advancements in medical management, ILD remains a challenging condition with limited treatment options ...
Komal, Acharya Rohit Om, Hardeep, Vedpriya Arya   +3 more
core   +1 more source

A Transgenic Rat Model of DXd ADC‐Related Interstitial Pneumonitis for Mechanistic and Translational Research

Cancer Science, EarlyView.
hTROP2 Tg rats exhibit key pathological and transcriptomic features of DXd ADC‐related ILD, supporting their utility as a translational model. Rat, alveolus, antibody illustrations were adapted from NIAID NIH BioArt Source. ABSTRACT Deruxtecan‐based antibody‐drug conjugates (DXd ADCs) provide substantial clinical benefit across multiple malignancies ...
Kazuyoshi Kumagai, Yuma Nagai, Yuji Shirai, Kazunori Fujimoto, Masako Imaoka, Katsuyoshi Chiba   +5 more
wiley   +1 more source

A Harmonised Approach to Curating Research-Ready Datasets for Asthma, Chronic Obstructive Pulmonary Disease (COPD) and Interstitial Lung Disease (ILD) in England, Wales and Scotland Using Clinical Practice Research Datalink (CPRD), Secure Anonymised Information Linkage (SAIL) Databank and DataLoch

Clinical Epidemiology
Sara Hatam,1,* Sean Timothy Scully,2,* Sarah Cook,3,* Hywel T Evans,2,* Alastair Hume,4 Constantinos Kallis,3 Ian Farr,2 Chris Orton,2 Aziz Sheikh,1 Jennifer K Quint3 1Usher Institute, The University of Edinburgh, Edinburgh, UK ...
Hatam S, Scully ST, Cook S, Evans HT, Hume A, Kallis C, Farr I, Orton C, Sheikh A, Quint JK   +9 more
doaj  

Peri-transplant frailty changes impact survival in interstitial lung diseases

ERJ Open Research
Background Frailty is a dynamic state of vulnerability resulting from progressive functional decline and multimorbidity in patients with interstitial lung disease (ILD).
Stefan Kuhnert, Sabina Guler, Luise Wilke, Janine Sommerlad, Silke Tello, Anita Windhorst, Andreas Guenther, Matthias Hecker, Ekaterina Krauss   +8 more
doaj   +1 more source

The interstitial lung disease patient pathway: from referral to diagnosis

ERJ Open Research
Background Suspected interstitial lung disease (ILD) patients may be referred to an ILD-specialist centre or a non-ILD-specialist centre for diagnosis and treatment.
Graham Lough, Rayid Abdulqawi, Gina Amanda, Katerina Antoniou, Arata Azuma, Milind Baldi, Ahmed Bayoumy, Jürgen Behr, Elisabeth Bendstrup, Demosthenes Bouros, Kevin Brown, Nazia Chaudhuri, Tamera J. Corte, Vincent Cottin, Bruno Crestani, Kevin R. Flaherty, Ian Glaspole, Leticia Kawano-Dourado, Michael P. Keane, Martin Kolb, Fernando J. Martinez, Maria Molina-Molina, Iñigo Ojanguren, Laurence Pearmain, Ganesh Raghu, Paola Rottoli, Stefan C. Stanel, Gabriela Tabaj, Carlo Vancheri, Brenda Varela, Bonnie Wang, Athol Wells, Pilar Rivera-Ortega   +32 more
doaj   +1 more source

Exosomal KL-6 surpasses total plasma KL-6 in the diagnosis of Interstitial Lung Disease (ILD)

Background Krebs Von den Lungen-6 (KL-6) is an established biomarker for interstitial lung diseases (ILDs), but the utility of exosomal KL-6 versus plasma KL-6 in connective tissue disease-associated ILD (CTD-ILD) remains unclear.
Jia Li, Ruogu Lai, Xinru Wei, Yunpeng Xiao, Jie Zhang, Qian Han, Yanting Fang, Jin Li, Junqi Li, Xiaoxiao Li, Huimin Huang, Jin Su, Ziyi Zhang, Baoqing Sun, Ping Zhang, Yunxin Lai, Shuilian Yu, Fei Yuan   +17 more
core   +1 more source

A screening tool to detect interstitial lung disease in systemic sclerosis: the ILD-RISC score [PDF]

ObjectivesAs a screening tool for the presence of systemic sclerosis-associated interstitial lung disease (SSc-ILD) on high-resolution computed tomography (HRCT) is missing, we aimed to develop the ILD-RISC score, a risk algorithm to guide physicians in ...
Matucci-Cerinic, M., Fretheim, H., Garaiman, A., Hoffmann-Vold, A.M., Vonk, M.C., Velauthapillai, A., Bruni, C., Liem, S.I.E., Bjorkekjær, H., Tofani, L., Becker, M.O., Vries-Bouwstra, J. de, Barua, I., Galetti, I., Distler, J.H.W., Distler, O.   +15 more
core   +1 more source

Optimizing diphenyl(2,4,6‐trimethylbenzoyl)phosphine oxide concentration and post‐curing time to balance mechanical properties and color stability in a three‐dimensional‐printed restorative resin

European Journal of Oral Sciences, EarlyView.
Abstract Three‐dimensional (3D) printing is widely used in dental restorations; however, optimization of photoinitiator concentration and post‐curing protocols remains critical to achieve a balance between mechanical and esthetic performance. This study evaluated the combined effect of diphenyl(2,4,6‐trimethylbenzoyl)phosphine oxide (TPO) concentration
Eloah Nunes de Almeida, Vinicius da Nóbrega Marques, Ido Luiz de Azevedo Feiten, André Luis Faria‐e‐Silva, Larissa Maria Cavalcante, Luis Felipe Schneider   +5 more
wiley   +1 more source