Results 61 to 70 of about 48,353 (157)

Drugs in focus: Budesonide and its role in paediatric gastrointestinal disorders

Journal of Pediatric Gastroenterology and Nutrition, Volume 82, Issue 1, Page 60-69, January 2026.
Abstract Budesonide is a glucocorticoid with strong topical anti‐inflammatory properties and minimal systemic effects due to extensive first‐pass hepatic metabolism. It is designed for targeted delivery within the gastrointestinal (GI) tract and is available in oral and rectal formulations.
Sohail Aziz, Maria Giovanna Puoti, Amit Assa, Zrinjka Misak, Emmanuel Mas, Osvaldo Borrelli, Jernej Dolinšek, Javier Martin‐de‐Carpi, Isabelle Scheers, Christos Tzivinikos, Matjaž Homan, Caterina Strisciuglio   +11 more
wiley   +1 more source

Ileal Atresia

, 2020
Ileal and jejunal atresias are usually described together as jejunoileal atresia (JIA). JIA is a common cause of intestinal obstruction in neonates. It is seen in 1 in 5000 to 1 in 14000 live births.
Rentea, Rebecca M, Osuchukwu, Obiyo O
core  

Fourth Ventricular Outflow Obstruction in an Infant with Ileal Atresia and Laryngomalacia: Endoscopic Management

Indian Journal of Neurosurgery, 2020
Fourth ventricle outflow obstruction (FVOO) is a rare cause of obstructive hydrocephalus. In this study, we described a case of idiopathic FVOO with ileal atresia and laryngomalacia which was managed with endoscopic third ventriculostomy (ETV) and re ...
Forhad H. Chowdhury, Mohammod Raziul Haque, Jalal Uddin Mohammod Rumi, Mohammod Samsul Arifin   +3 more
doaj   +1 more source

Intestinal and Multivisceral Transplantation: Where We Stand Today

Pediatric Transplantation, Volume 30, Issue 1, January 2026.
ABSTRACT Intestinal and multivisceral transplantation has evolved from an experimental to a life‐saving procedure for children and adults with complications of gut failure (GF). Suboptimal long‐term outcomes of transplant elicit recent advances in surgical and medical gut rehabilitation along with the introduction of glucagon‐like peptide‐2 (GLP‐2 ...
Mohamed Maklad, Mohammed Osman, Mariam Ismail, Tetsuya Tajima, Kadakkal Radhakrishnan, Masato Fujiki   +5 more
wiley   +1 more source

PPP1R12A Mutation Presenting With Congenital Jejunal Atresia and Short Stature: A Pediatric Endocrinology Case Report

Case Reports in Pediatrics, Volume 2026, Issue 1, 2026.
We report an 11‐year‐old Hispanic male with a PPP1R12A gene de novo heterozygous likely pathogenic mutation, p. (Gln13Arg) (CAG>CGG), c.38 A > G in Exon 1 (NM_002480.2), detected on whole‐exome trio sequencing during his short‐stature evaluation.
Rosita Saul, Maya David, Jordin Frasch, Pedro A. Sanchez-Lara, Bahareh M. Schweiger, Andrea Scaramuzza   +5 more
wiley   +1 more source

Jejunoileal atresia and cystic fibrosis: don’t miss it

BMC Research Notes, 2012
Background While an increased prevalence of cystic fibrosis (CF) in patients with jejunal atresia and ileal atresia (JIA) has been described previously, it still may not be a practice routine to indicate a sweat test or DNA test for CFTR mutations in ...
Siersma Carolien L, Rottier Bart L, Hulscher Jan BF, Bouman Katelijne, van Stuijvenberg Margriet   +4 more
doaj   +1 more source

Living Donor Intestinal Transplant: Indication, Techniques, Surgical Complications, and Outcomes in Recipients and Donors: A Systematic Review

Journal of Transplantation, Volume 2026, Issue 1, 2026.
Background Living donor intestinal transplantation (LDITx) is an alternative option to cadaveric transplants as a last resort in treating intestinal failure. There are limited data on LDITx outcomes. This systematic review evaluates LDITx in terms of indications, contraindications, surgical complications, and patient outcomes.
Adil Nusair, Saad Bin Yousuf, Ahmed Adham R. Elsayed, Marc D. Basson, Richa Sharma   +4 more
wiley   +1 more source

Apple-peel atresia presenting as foetal intestinal obstruction

African Journal of Paediatric Surgery, 2011
Apple-peel atresia or Type 3 jejuno-ileal atresia (JIA) is an uncommon cause of foetal intestinal obstruction. Bowel obstruction in the foetus is diagnosed on the prenatal ultrasonography only in 50% cases.
Ashok Yadavrao Kshirsagar, Sushma Rajaram Desai, Mayur Anant Nagvekar, Gaurav Om Prakash Vasisth   +3 more
doaj   +1 more source

The Role of APOL1 in Necrotizing Enterocolitis and Its Promise as a Diagnostic Biomarker

Mediators of Inflammation, Volume 2026, Issue 1, 2026.
Objective Necrotizing enterocolitis (NEC) is a severe inflammatory disease of the intestine. Although previous studies have demonstrated that APOL1 plays an important role in regulating macrophage polarization and immune‐mediated inflammatory diseases, its specific function in NEC remains unclear.
Jie-Ting Lu, Qiu-Hua Wang, Ying-Yan Liu, Song Tian, Long-Long Hou, Xin Zhong, Li-Zhu Chen, Qian Zhang, Peng-Fei Wei, Lin Li, Yan Tian, Qiu-Ming He, Yu-Feng Liu, Gen-Quan Yin, Yu Ouyang, Lin Liao, Wei Zhong, Chao-Ting Lan, Oscar Medina-Contreras   +18 more
wiley   +1 more source

Genotype–Phenotype Correlation in TTC7A ‐Associated Gastrointestinal Defects and Immunodeficiency Syndrome 1

American Journal of Medical Genetics Part A, Volume 197, Issue 12, December 2025.
ABSTRACT Gastrointestinal defects and immunodeficiency syndrome 1 (GIDID1) is a rare autosomal recessive disorder caused by biallelic variants in TTC7A. GIDID1 is characterized by a broad clinical spectrum ranging from very early‐onset inflammatory bowel disease (VEOIBD) to multiple intestinal atresia (MIA) with or without immunological manifestations.
Julia Imhoff, Hans Christian Schmidt, Matthias Hans Belau, Johanna Hagens, Mario Lange, Daniel Tegtmeyer, Konrad Reinshagen, Frederike Leonie Harms, Christian Tomuschat   +8 more
wiley   +1 more source