Results 81 to 90 of about 12,665 (227)
Chromogranin A: From Laboratory to Clinical Aspects of Patients with Neuroendocrine Tumors [PDF]
, 2018 Background. Neuroendocrine tumors (NETs) are characterized by having behavior and prognosis that depend upon tumor histology, primary site, staging, and proliferative index.
Baldelli, Roberto +8 more
core +1 more source
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Guanylate cyclase‐C (GC‐C) is the receptor for endogenous (uro)guanylin peptides, bacterial toxins and pharmacological analogues. Receptor activation leads to intestinal fluid loss, but also activates an antiproliferative pathway and is a promising target in colorectal cancer therapy.
Renjie Xiu +4 more
wiley +1 more source
A massive abdominal wall desmoid tumor occurring in a laparotomy scar: A case report [PDF]
, 2011 Introduction Desmoid tumors are benign but locally aggressive tumors of mesenchymal origin which are poorly circumscribed, infiltrate the surrounding tissue, lack a true capsule and are composed of abundant collagen.
Joseph K Wanjeri, Collins JO Opeya
core +2 more sources
Histopathology, EarlyView.We report a series of 12 patients (mean age 63 years) with chronic oesophageal ulceration showing morphological features of IgG4‐related inflammatory disease. Most patients underwent several rounds of endoscopy until this association was recognized. The majority of patients went into clinical and histological remission following corticosteroid therapy.
Hanna Henzinger +5 more
wiley +1 more source
Prognostic factors in primary adenocarcinoma of the small intestine: 13-year single institution experience [PDF]
, 2008 Background Adenocarcinoma of the small bowel is a relatively rare malignancy as compared to the other malignancies of the gastrointestinal tract. Nonspecific presentation and infrequent occurrence often leads to a delay in diagnosis and consequent poor ...
Kongkrit Chaiyasate +4 more
core +2 more sources
The Oral‐Gut Axis: Bidirectional Interactions Between Microbiome and Diseases
Journal of Periodontal Research, EarlyView.This study aims to summarize the mechanisms underlying ectopic colonization of the gut by oral pathobionts and the microbial and host factors that regulate this process. ABSTRACT Increased colonization of typically oral microorganisms is frequently observed in the gut mucosa or lumen of individuals with gastrointestinal disorders, including patients ...
Shinya Ebihara, Nobuhiko Kamada
wiley +1 more source
The role of neutrophils in the pathophysiology of inflammatory bowel diseases
Periodontology 2000, EarlyView.Abstract Objectives Inflammatory bowel disease (IBD) encompasses a spectrum of chronic disorders of the gastrointestinal tract, with a potential bidirectional relationship with periodontitis. Neutrophils are key regulators of immune‐inflammatory responses and play a major role in both diseases.
Joao Paulo Steffens +8 more
wiley +1 more source
Novel MYH11::GLI3 fusion in ileal leiomyoma
Pathology and Oncology ResearchBackgroundLeiomyomas of the gastrointestinal tract (GI) are benign smooth muscle neoplasms with limited genetic characterization. Molecular investigations may improve diagnostic classification and enhance understanding of their biological behavior ...
Ioannis Panagopoulos +2 more
doaj +1 more source
Exome-wide somatic mutation characterization of small bowel adenocarcinoma [PDF]
, 2018 Small bowel adenocarcinoma (SBA) is an aggressive disease with limited treatment options. Despite previous studies, its molecular genetic background has remained somewhat elusive.
A Laforest +77 more
core +5 more sources