Results 151 to 160 of about 125,946 (236)

Impact of Housing on Burn Injury Patterns and Outcomes: A Retrospective Cohort Study at a Canadian Burn Center. [PDF]

J Burn Care Res
Lee JJ, Sattar I, Harrop S, Schimmel T, Dodd SX, Manchikanti S, Wong JN, Armour A.   +7 more
europepmc   +1 more source

An Activity‐Dependent NEPAS–PTX3 Axis Links Neurovascular and Myelin Deficits to Cognitive Impairment

Advanced Science, EarlyView.
An activity‐dependent pathway links prefrontal circuit hypoactivity to cognitive impairment. Reduced PVA–mPFC activity upregulates NEPAS, which suppresses PTX3 secretion, leading to impaired angiogenesis, myelin deficits, and memory decline. Rescue is achieved by NEPAS knockdown or chemogenetic circuit activation.
Boya Hu, Zifei Chen, Bingmei Sun, Jiale Gao, Jiale Xu, Xiaochun Guo, Fenfei Gao, Zhongsi Wang, Jie Wu, Xiaoyu Ji, Peipei Liu, Bing Huang   +11 more
wiley   +1 more source

Addressing Employment Barriers Among Persons with Homeless Experiences: Implementation Lessons For Advancing Equity From an Electronic-Bicycle-Supported Vocational Rehabilitation Pilot. [PDF]

J Prim Care Community Health
Panadero TJ, Castellon MO, Jacobo EM, Stigers PJ, Raja P, Gabrielian SE.   +5 more
europepmc   +1 more source

Hepatocyte BDNF Acts as a Novel Immune Checkpoint to Restrain TLR4‐Mediated Acute Hepatitis

Advanced Science, EarlyView.
This study identifies hepatocyte‐derived BDNF as an endogenous TLR4 antagonist that alleviates acute hepatitis. BDNF is downregulated in hepatocytes via REST‐mediated transcriptional repression during ALI/ALF. Mechanistically, BDNF binds to TLR4 on macrophages to suppress inflammation.
Weiwei Zhu, Yaqian Cui, Yongqiang Zhou, Yihui Zheng, Lijiang Huang, Leiming Jin, Qianhui Zhang, Pan Chen, Mengsha Lin, Jiaxi Ye, Yongqiang Xiong, Joo Young Huh, Xiang Hu, Xiaokun Li, Wu Luo, Guang Liang   +15 more
wiley   +1 more source

Influence of Housing Status on Health Outcomes for Reproductive-Age Women With and Without HIV in the Southern United States. [PDF]

J Acquir Immune Defic Syndr
Ganguly S, Christman O, Yang Q, Mehta CC, Tisdale TT, Fujita AW, Konkle-Parker DJ, Alcaide ML, Rana A, Kassaye SG, Topper EF, Westreich D, Sheth AN.   +12 more
europepmc   +1 more source

From Displacement to Hope: A Guide for Displaced Indigenous Communities and Host Communities [PDF]

, 2017
Chrétien, Annette, Murphy, Brenda, Pearce, Laurie   +2 more
core   +1 more source

Persistently Increased Expression of PKMzeta and Unbiased Gene Expression Profiles Identify Hippocampal Molecular Traces of a Long‐Term Active Place Avoidance Memory and “Shadow” Proteins

Advanced Science, EarlyView.
Protein complexes like KIBRA‐PKMζ are crucial for maintaining memories, forming month‐long protein traces in memory‐tagged neurons, but conventional RNA‐seq analysis fails to detect their transcript changes, leaving memory molecules undetected in the shadows of abundantly‐expressed genes.
Jiyeon Han, Alejandro Grau‐Perales, Rayna M. Harris, Edith Lesburguères, Hsin‐Yi Kao, Asit Pal, Juan Marcos Alarcon, Todd C. Sacktor, Stefano Martiniani, Hans A. Hofmann, André A. Fenton   +10 more
wiley   +1 more source

Health care needs survey to improve preparedness of community outreach clinics after severe flooding in Mulanje district, Malawi. [PDF]

PLOS Glob Public Health
Njala J, Balakasi K, Phiri K, Chimbaka H, Makwaya A, Smith D, Songo J, Mphande M, Njikho L, Chinkonde JR, Worku A, Dovel K, Phiri S, van Oosterhout JJ.   +13 more
europepmc   +1 more source

Cancer‐Associated Fibroblasts Promote Tumor Immunosuppression in Hepatocellular Carcinoma via the NNMT‐ANGPTL4 Axis

Advanced Science, EarlyView.
ABSTRACT Background & Aims: Cancer‐associated fibroblasts (CAFs) drive immunosuppression in hepatocellular carcinoma (HCC). However, their metabolic regulation remains poorly defined. We investigated the role of nicotinamide N‐methyltransferase (NNMT) in CAFs. Approach & Results: High NNMT expression in CAF tissues was confirmed by western blotting and
Shounan Lu, Shanjia Ke, Hongjun Yu, Zhanzhi Meng, Miaoyu Bai, Yanan Xu, Hui Zhu, Jinwen Yang, Baolin Qian, Bing Yin, Chaoqun Wang, Zhigang Feng, Zhongyu Li, Yongzhi Zhou, Zihao Li, Xinglong Li, Yongliang Hua, Yao Fu, Wei Tang, Yaohua Wu, Yong Ma   +20 more
wiley   +1 more source

Comparative treatment of homeless persons with an infectious disease in the US emergency department setting: a retrospective approach. [PDF]

J Epidemiol Community Health
Barnes J, Segars L, Wasserman JA, Karabon P, Taylor TAH.   +4 more
europepmc   +1 more source