Results 41 to 50 of about 988,939 (305)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Regularization of nonlinear Ill-posed equations with accretive operators

open access: yesFixed Point Theory and Applications, 2005
We study the regularization methods for solving equations with arbitrary accretive operators. We establish the strong convergence of these methods and their stability with respect to perturbations of operators and constraint sets in Banach spaces.
H. Zegeye, C. E. Chidume, Ya. I. Alber
doaj   +2 more sources

Quasireversibility for inhomogeneous ill-posed problems in Hilbert spaces

open access: yesElectronic Journal of Differential Equations, 2010
In a Hilbert space $mathcal{H}$, the inhomogeneous ill-posed abstract Cauchy problem is given by $frac{du}{dt} = Au(t) + h(t)$, $u(0) = chi$, $0 leq t < T$; where $A$ is a positive self-adjoint linear operator acting on $mathcal{H}$, $chi in ...
Beth M. Campbell Hetrick
doaj  

Chebyshev polynomials to Volterra-Fredholm integral equations of the first kind

open access: yesREMAT
Numerous methods have been studied and discussed for solving ill-posed Volterra integral equations and ill-posed Fredholm integral equations, but rarely for both simultaneously.
Mohamed Nasseh Nadir, Adel Jawahdou
doaj   +1 more source

Minimum Principles for Ill-Posed Problems [PDF]

open access: yesSIAM Journal on Mathematical Analysis, 1978
Ill-posed problems $Ax = h$ are discussed in which A is Hermitian and postive definite; a bound $\| {Bx} \| \leqq \beta $ is prescribed. A minimum principle is given for an approximate solution $\hat x$. Comparisons are made with the least-squares solutions of K. Miller, A. Tikhonov, et al.
openaire   +2 more sources

Unique continuation and continuous dependence results for a severely ill-posed integro-differential parabolic problem

open access: yes, 2012
Via Carleman estimates we determine sufficient conditions ensuring uniqueness and continuous dependence results for a severely ill-posed linear integro-differential boundary-value parabolic problem with no initial condition.
A. Lorenzi, F. Messina
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

STABILITY ESTIMATE FOR THE HEAT EQUATION BACKWARD IN TIME WITH NEUMANN AND INTEGRAL BOUNDARY CONDITIONS

open access: yesTạp chí Khoa học
In this paper, we first prove that the heat equation backward in time with Neumann and integral boundary conditions is an ill-posed problem. Then, we establish a stability estimate of Hölder type for this ill-posed problem.
Nguyen Van Duc
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

IAASNet: Ill-Posed-Aware Aggregated Stereo Matching Network for Cross-Orbit Optical Satellite Images

open access: yesRemote Sensing
Stereo matching estimates disparity by finding correspondences between stereo image pairs. Under ill-posed conditions such as geometric differences, radiometric differences, and temporal changes, accurate estimation becomes difficult due to insufficient ...
Jiaxuan Huang, Haoxuan Sun, Taoyang Wang
doaj   +1 more source

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