Results 101 to 110 of about 29,061 (317)

A nonhomogeneous backward heat problem: Regularization and error estimates

open access: yesElectronic Journal of Differential Equations, 2008
We consider the problem of finding the initial temperature, from the final temperature, in the nonhomogeneous heat equation $$displaylines{ u_t-u_{xx}= f(x,t),quad (x,t)in (0,pi)imes (0,T),\ u(0,t)= u(pi,t)= 0, quad (x,t) in (0,pi)imes(0,T ...
Trong Dang Duc, Huy Tuan Nguyen
doaj  

Universal Solvent Escape Strategies for Efficient Curing of Hydrogen‐Bond‐Rich 3D Printing Inks

open access: yesAdvanced Science, EarlyView.
This study developed a new 3D printing method for hydrogen‐bonded polymers by combining solvent replacement, nanoparticles, and optimized printing paths. This allows fast, precise scaffold fabrication. The scaffolds can be easily customized and release therapeutic agents slowly through protonation, enabling personalized bone, blood vessel, and nerve ...
Jie Chen   +11 more
wiley   +1 more source

CACLENS: A Multitask Deep Learning System for Enzyme Discovery

open access: yesAdvanced Science, EarlyView.
CACLENS, a multimodal and multi‐task deep learning framework integrating cross‐attention, contrastive learning, and customized gate control, enables reaction type classification, EC number prediction, and reaction feasibility assessment. CACLENS accelerates functional enzyme discovery and identifies efficient Zearalenone (ZEN)‐degrading enzymes.
Xilong Yi   +5 more
wiley   +1 more source

An inverse problem in a parabolic equation

open access: yesElectronic Journal of Differential Equations, 1998
In this paper, an inverse problem in a parabolic equation is studied. An unknown function in the equation is related to two integral equations in terms of heat kernel. One of the integral equations is well-posed while another is ill-posed.
Zhilin Li, Kewang Zheng
doaj  

Mechanisms of Aristolochic Acid Resistance in Specialist Butterflies and Evolutionary Insights for Potential Protective Pathways

open access: yesAdvanced Science, EarlyView.
The study provides an extreme example of insect adaptation to highly toxic defenses of host plants, and investigates the complex strategies to resist carcinogenic aristolochic acids, including physical isolation, metabolic detoxification, and DNA repair.
Yang Luan   +20 more
wiley   +1 more source

Generating Dynamic Structures Through Physics‐Based Sampling of Predicted Inter‐Residue Geometries

open access: yesAdvanced Science, EarlyView.
While static structure prediction has been revolutionized, modeling protein dynamics remains elusive. trRosettaX2‐Dynamics is presented to address this challenge. This framework leverages a Transformer‐based network to predict inter‐residue geometric constraints, guiding conformation generation via physics‐based iterative sampling. The resulting method
Chenxiao Xiang   +3 more
wiley   +1 more source

Engineered Small Extracellular Vesicles Targeting Tumor‐Associated Endothelial Cells to Effectively Remodel the Glioma Microenvironment

open access: yesAdvanced Science, EarlyView.
This study developed a novel drug delivery platform that overcomes the blood‐brain barrier in glioblastoma. By fusing IGFBP7 with small extracellular vesicles, the platform specifically targets tumor vasculature. It effectively delivers temozolomide, suppressing tumor growth at low doses.
Lingling Liu   +17 more
wiley   +1 more source

A Numerical Method for Backward Inverse Heat Conduction Problem With two Unknown Functions

open access: yesInternational Journal of Industrial Engineering and Production Research, 2006
This paper considers a linear one dimensional inverse heat conduction problem with non constant thermal diffusivity and two unknown terms in a heated bar with unit length.
A. Shidfar, Ali Zakeri
doaj  

Calculation Method for the Relaxation Time Spectra of Viscoelastic Fluids Using Dynamic Moduli

open access: yesJournal of Applied Science and Engineering
The influence of different error functions (standard deviation, normalized standard deviation, and chi-square) as objective functions in the calculation of the relaxation time spectrum is studied, as well as the influence of different minimization ...
Luis Hamel, Sergio D. Rosales-Anzola
doaj   +1 more source

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