Results 91 to 100 of about 7,949,694 (307)

International differences in home treatment for mental health problems. Results of a systematic review.

open access: yes, 2002
BACKGROUND: It is perceived that North American home treatment studies reveal greater success in reducing days in hospital than do European studies. There are difficulties in extrapolating findings internationally.
Henderson, J   +11 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Improved care for teens in trouble with drugs, alcohol, and crime: Reclaiming Futures treatment providers advocate for change [PDF]

open access: yes, 2007
Children and teens with substance abuse problems desperately need treatment tailored to their age group, as recent studies on adolescent brain development have underscored. In the past few years, research has been conducted on how to treat this age group,
Reclaiming Futures Treatment Fellowship
core  

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Factors that influence on the decisions of battered women

open access: yesNURE Investigación, 2008
Violence towards and against women consists in any kind of violation of woman’s personality, her physical integrity or her freedom of movement. Nowadays, gender-based violence is considered a state and public health problem as well as a social concerning
Juana Robledo Martín   +3 more
doaj  

Frequently Ill Child Syndrome

open access: yesАнтибиотики и Химиотерапия, 2020
The efficacy of cycloferon use in the treatment of frequently ill children (FIC) was estimated by the dynamics of the blood plasma proteomic profile. A group of FIC at the age of 4 to 10 years were observed.
M. G. Romantsov   +2 more
doaj  

VIOLENCE AGAINST THE ELDERLY: AN OLD STIGMA

open access: yesCogitare Enfermagem, 2011
This descriptive study with a qualitative approach aimed to investigate the situations of violence against elderly residents of an area served by a Basic Health Unit of the Family Health Strategy in the North-East region of Rio Grande do Sul, Brazil. The
Cristiane Zamboni   +3 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Homeownership and ill-being [PDF]

open access: yes
Social policy aims to relieve the ill-being of low income groups, and housing policies in many European countries promote homeownership for low-income households.
Bloze, Gintautas, Skak, Morten
core  

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

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