Results 261 to 270 of about 1,311,956 (360)

piR‐RCC Suppresses Renal Cell Carcinoma Progression by Facilitating YBX‐1 Cytoplasm Localization

Advanced Science, EarlyView.
PIWI‐interacting RNAs (piRNAs), a novel category of small non‐coding RNAs, have been implicated in the development of various diseases. This study explores the tumor‐suppressive mechanism of a downregulated piRNA (designated piR‐RCC) in renal cell carcinoma (RCC), and provides a delivery strategy targeting RCC tumor by constructing a cell membrane ...
Ruyue Wang, Fan Li, Yudong Lin, Zeyi Lu, Wenqin Luo, Zhehao Xu, Ziwei Zhu, Yi Lu, Xudong Mao, Yang Li, Zhinian Shen, Haohua Lu, Yining Chen, Liqun Xia, Mingchao Wang, Lifeng Ding, Gonghui Li   +16 more
wiley   +1 more source

Illumina MiSeq Sequencing Reveals Diverse Microbial Communities of Activated Sludge Systems Stimulated by Different Aromatics for Indigo Biosynthesis from Indole

, 2015
Xuwang Zhang, Yuanyuan Qu, Qiao Ma, Zhaojing Zhang, Duanxing Li, Jingwei Wang, Wenli Shen, Emily S. Shen, Jiti Zhou   +8 more
openalex   +2 more sources

Illumina Sequencing in Conjunction with Propidium Monoazide to Identify Live Bacteria After Antiseptic Treatment in a Complex Oral Biofilm: A Study Using an Ex Vivo Supragingival Biofilm Model. [PDF]

Antibiotics (Basel)
Sánchez MC, Hernández P, Velapatiño Á, Cuba E, Ciudad MJ, Collado L.   +5 more
europepmc   +1 more source

Complete Reference Genome Sequence of the Extensively Drug-Resistant Strain Neisseria gonorrhoeae AT159, with Ceftriaxone Resistance and High-Level Azithromycin Resistance, Using Nanopore Q20+ Chemistry and Illumina Sequencing. [PDF]

Microbiol Resour Announc, 2022
Golparian D, Pleininger S, Jacobsson S, Indra A, Unemo M.   +4 more
europepmc   +1 more source

RIG‐I‐Inducing Small Molecules Potently Inhibit HMA‐Resistant AML Through Igniting the Overloaded dsRNA Arsenal

Advanced Science, EarlyView.
This study reveals a novel mechanism of resistance to DNA hypomethylating agents (HMAs) in acute myeloid leukemia (AML), and identifies all‐trans retinoic acid (ATRA) and tamibarotene (TAM) as potent agents that overcome HMA resistance by reactivating the interferon anticancer immune response. The findings offer promising therapeutic strategies for HMA‐
Xueqin Chen, Jiaqi Wu, Yuntong Li, Jiayu Huang, Xiangqin Weng, Jiale Wu, Shujun Xiao, Huaxin Song, Zhengyuan Wang, Ni Yan, Fangfang Shi, Derun Zheng, Kai Tan, Hesong Zhang, Jingyi Cui, Wen Wu, Wei Wu, Sujiang Zhang, Min Lu   +18 more
wiley   +1 more source

Strategy and Performance Evaluation of Low-Frequency Variant Calling for SARS-CoV-2 Using Targeted Deep Illumina Sequencing. [PDF]

Front Microbiol, 2021
Van Poelvoorde LAE, Delcourt T, Coucke W, Herman P, De Keersmaecker SCJ, Saelens X, Roosens NHC, Vanneste K.   +7 more
europepmc   +1 more source

Dynein‐Dependent Endo‐Lysosomal Degradation Drives Lewy Body Disorders Accompanied by Aβ Pathology

Advanced Science, EarlyView.
This study investigates the impact of Aβ plaques on α‐synuclein (αSyn) pathologies in dementia with Lewy bodies (DLB). Co‐culturing primary neurons with AD mouse brain slices reveals impaired dynein‐dependent organelle trafficking, affecting αSyn degradation. Activating Rab7 restores this process, reducing αSyn inclusions.
Linlin Zhou, Yuwei Wang, Yu Liu, Feipeng Zhu, Ge Gao, Chengjie Li, Pu Ai, Jingying Xu, Junxin Wang, Long Guo, Yuting Guan, Virginia Man‐Yee Lee, Jianjun Chen, Jialin Zheng, Qihui Wu   +14 more
wiley   +1 more source

Improved DNA Extraction and Illumina Sequencing of DNA Recovered from Aged Rootless Hair Shafts Found in Relics Associated with the Romanov Family. [PDF]

Genes (Basel), 2022
Loreille O, Tillmar A, Brandhagen MD, Otterstatter L, Irwin JA.   +4 more
europepmc   +1 more source

H3K36me3‐Guided m6A Modification of Oncogenic L1CAM‐AS1 Drives Macrophage Polarization and Immunotherapy Resistance in Hepatocellular Carcinoma

Advanced Science, EarlyView.
L1CAM‐AS1 is identified as a novel H3K36me3‐guided, m6A‐modified long noncoding RNA (lncRNA) in hepatocellular carcinoma (HCC) cells. L1CAM‐AS1 stabilizes RAN protein, enhances M2 macrophages‐released CCL5‐induced nuclear import of RELA, activates the NF‐κB signaling, up‐regulates CCL2 expression and secretion from HCC cells, and enhances M2 ...
Teng Wang, Linyu Han, Yanfei Huo, Long Zhang, Yizhou Huang, Nasha Zhang, Ming Yang   +6 more
wiley   +1 more source

Diversity of soil fungi from sacred groves of Kerala, India revealed by comparative metagenomics analysis using illumina sequencing. [PDF]

3 Biotech
Nandakumar K, Anto PV, Antony I.
europepmc   +1 more source