Results 61 to 70 of about 1,741,443 (291)

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

open access: yesFEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Subclinical Optic Nerve Involvement in Radiologically Isolated Syndrome: Multimodal Detection and Diagnostic Impact

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay   +13 more
wiley   +1 more source

Enhancing multi-spot structured illumination microscopy with fluorescence difference [PDF]

open access: yesRoyal Society Open Science, 2018
Structured illumination microscopy is a super-resolution technique used extensively in biological research. However, this technique is limited in the maximum possible resolution increase.
Edward N. Ward   +2 more
doaj   +1 more source

Anorectal Dysfunction in Systemic Sclerosis: Clinical Phenotypes and Functional Patterns

open access: yesArthritis Care &Research, EarlyView.
Objective The aim of this study was to characterize specific physiologic defects in anorectal dysfunction in systemic sclerosis (SSc) using anorectal manometry (ARM), evaluate associations with gastrointestinal (GI) and extraintestinal clinical phenotypes, and explore potential serologic markers for risk stratification.
Timothy Kaniecki   +6 more
wiley   +1 more source

Illuminant estimation as cue combination

open access: yesJournal of Vision, 2002
This work briefly describes a model for illuminant estimation based on combination of candidate illuminant cues. Many of the research issues concerning cue combination in depth and shape perception translate well to the study of surface color perception.
openaire   +2 more sources

Employment Trajectories of Patients With Systemic Lupus Erythematosus and Factors Driving Transitions Between States

open access: yesArthritis Care &Research, EarlyView.
Objective Systemic lupus erythematosus (SLE) significantly impacts employment capacity. This study aimed to investigate the impact of burden of disease activity, damage, and treatment on employment outcomes and transitions in patients with SLE. Methods Using data from a single center, we analyzed employment transitions, adjusted mean disease activity ...
Javier Mencia‐Ledo   +4 more
wiley   +1 more source

Illumination invariant face recognition based on dual‐tree complex wavelet transform

open access: yesIET Computer Vision, 2015
This study presents a new dual‐tree complex wavelet transform (DT‐CWT)‐based illumination normalisation approach for face recognition under varying lighting conditions. The method consists of three steps.
Haifeng Hu
doaj   +1 more source

A method for estimating the errors in many-light rendering with supersampling

open access: yesComputational Visual Media, 2019
In many-light rendering, a variety of visual and illumination effects, including anti-aliasing, depth of field, volumetric scattering, and subsurface scattering, are combined to create a number of virtual point lights (VPLs).
Hirokazu Sakai   +3 more
doaj   +1 more source

Psychophysical estimation of the best illumination for appreciation of Renaissance paintings

open access: yes, 2006
A variety of light sources are used in museum environments where the main concern is to prevent damaging effects of the light on paintings. Yet, the visual impression of an artistic painting is strongly influenced by the intensity and spectral profile of
Nascimento, Sérgio M. C.   +3 more
core   +1 more source

High‐Temperature Phase Transformation in a V‐9Si‐6.5B Alloy: The Kinetic and Crystallographic Pathway From V5SiB2 to V8SiB4

open access: yesAdvanced Engineering Materials, EarlyView.
In situ synchrotron high‐energy X‐ray diffraction reveals the real‐time high‐temperature phase evolution of a ternary V‐9Si‐6.5B alloy. The study uncovers a kinetically delayed V5SiB2 → V8SiB4 transformation governed by massive structural and chemical barriers.
Zahra Sabeti   +4 more
wiley   +1 more source

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