Results 91 to 100 of about 2,327,854 (296)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Adaptive Equi-Energy Sampler : Convergence and Illustration

open access: yes, 2013
Markov chain Monte Carlo (MCMC) methods allow to sample a distribution known up to a multiplicative constant. Classical MCMC samplers are known to have very poor mixing properties when sampling multimodal distributions.
Fort, Gersende   +2 more
core  

Flexible thermal device [PDF]

open access: yes, 1972
Fabrication of expansion joint, vibration isolator device with sufficient cross sectional area for high thermal conductivity is discussed. Device consists of multiple layers of metal foil which may be designed to meet specific applications. Thermodynamic
Elliott, D. H., Wallace, S. D.
core   +1 more source

Recursive representation of the torus 1-point conformal block

open access: yes, 2009
The recursive relation for the 1-point conformal block on a torus is derived and used to prove the identities between conformal blocks recently conjectured by R. Poghossian.
A Marshakov   +14 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Architecture and Visual Narrative

open access: yesProceedings, 2017
Architecture communication tools have been implemented in recent history by strategies and narrative artifices imported from cinema, comic, photo-journalism and infographic. The architect has integrated the traditional encoded drawing with more extensive
Fabio Quici
doaj   +1 more source

Medical Literary Messenger (Vol. 4, No. 1, Fall/Winter 2016) [PDF]

open access: yes, 2016
Irene—London, December 2006 / Katharine Harer -- Today / Antonia Lewandowski -- The Bench / Richard LeBlond -- illustration / Alana Barrett -- After Reading Elizabeth Bishop’s “In the Waiting Room” / Nina Bannett -- How to Open Your Eyes / Angus Woodward

core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Intersociety Literacy Comparisons [PDF]

open access: yes
literates, isolated illiterates, proximate illiterates, literacy measures, illustration, policy ...
Chakravarty, Satya R., Majumder, Amita
core  

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