Results 101 to 110 of about 2,327,854 (296)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
StrenaeImages play an essential role in the Père Castor project. Paul Faucher was as concerned about the quality of the texts as he was about the artistic dimension of the images, convinced that illustrated books encourage children to read and influence their ...
Christine Plu
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
‘Where is the Prince?’ Unlocking Doré’s Illustration of Perrault’s Cinderella
Relief: Revue Électronique de Littérature Francaise, 2010 This article proposes to consider illustrations as “intersemiotic translation” from words into images. Using this methodology, illustrations give particular insights into the reception and interpretation of Perrault’s fairy tales in a specific cultural ...
Emilie Sitzia
doaj
Nonperturbative corrections from an s-channel approach
, 2008 We report on studies of multi-parton corrections from nonlocal operator expansion. We discuss relations between eikonal-line matrix elements and parton distributions, and present an illustration for initial-state collinear evolution.Comment ...
Hautmann, F.
core
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Cahiers Victoriens et EdouardiensWilliam Robinson (1838‒1935) was one of the most influential gardeners of the Victorian period. His publishing empire in particular can be considered as one of the strongest impetuses that fostered the self-definition of the British people as a nation of
Aurélien Wasilewski
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, 1972 Development of time of flight mass spectrometer using laser powered vaporization source is discussed. Operation of equipment to measure thermal velocities of individual mass species is described.
Lincoln, K. A.
core +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source