Results 71 to 80 of about 929,241 (356)

The Literature ‘from’ Childhood: A New Epistemological Frontier with which to Read and Look at Books for Children

Encyclopaideia
The paper investigates, first of all, the epistemological status of one of the most elusive, yet vital, genres of literature, that aimed at childhood and adolescence. The “for” or “of” with which reference is made to the literature also known as ” youth”
Simone di Biasio
doaj   +1 more source

Le città invisibili nell’immaginario di Italo Calvino e nelle immagini di Pedro Cano

Italies, 2012
Le città invisibili di Italo Calvino sono servite da spunto all’omonimo ciclo di acquerelli dell’artista italo-iberico Pedro Cano, esposto con grande successo, pubblico e di critica, in varie sedi italiane e spagnole.
Alina Kreisberg
doaj   +1 more source

A Comparison on illustration of story and narration of illustration [PDF]

SHS Web of Conferences, 2018
The purpose of Turkish classes is to equip students with the ability of comprehension and narration. Everyone knows that stories covered in Turkish courses are offered with visuals, meaning pictures, so that they could be more easily understood. Illustration of a read story and narration of a picture shown can help explore the extent to which the topic
openaire   +2 more sources

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Illustrated Philosophical stories from Norwegian children and youth literature translated into Slovak after 2010

Journal of Language and Cultural Education, 2018
Among the artistically valuable philosophical stories with illustration which have been translated into Slovak from Norwegian literature for children and youth since 2010 are the books of Jostein Gaarder (Knižka otázok / English –Questions Asked, 2013 ...
Petríková Martina
doaj   +1 more source

Problems with Permatrace: a note on digital image publication

Internet Archaeology, 2004
The methodology presented here developed out of work required to convert the hard-copy illustrations submitted to Internet Archaeology for publication of the 1975 excavations at Cricklade.
Guy Hopkinson, Judith Winters
doaj   +1 more source

Vignette: interactive texture design and manipulation with freeform gestures for pen-and-ink illustration

International Conference on Human Factors in Computing Systems, 2012
Vignette is an interactive system that facilitates texture creation in pen-and-ink illustrations. Unlike existing systems, Vignette preserves illustrators' workflow and style: users draw a fraction of a texture and use gestures to automatically fill ...
Rubaiat Habib Kazi, T. Igarashi, Shengdong Zhao, Richard C. Davis   +3 more
semanticscholar   +1 more source