Results 91 to 100 of about 991,933 (306)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
The Role of Illustrations in Popularizing Medical Discourse
Linguae &: Rivista di Lingue e Culture Moderne, 2016 This article deals with illustrations in popularizing medical discourse. This visual tool can be considered as a strategy of paraphrasing, since popularizing journalists simplify and make information more explicit by using other semiotic information ...
Alida Maria Silletti
doaj +1 more source
A Perspective on Transformative Leadership and African American Women in History [PDF]
, 2015 The work of African American women as leaders historically has gone unnoticed or its impact has been underrepresented. This essay presents a discussion of transformative leadership and examples of three notable African American women who, through their ...
Bonaparte, Yvette Lynne
core +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The William Blake Archive (Upgrade)
RIDE, 2017 This review addresses the redesign of the William Blake Archive (WBA), which launched 12 December 2016, updating our previous review of the Archive, published in early 2017.
Kendal Crawford, Michelle Levy
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Mesure et Évaluation en Éducation, 2017 L’interprétation et la décision psychométriques reposent toutes deux sur la confrontation entre le score obtenu par le répondant et la norme (ou l’échelle normative) par laquelle on veut le situer dans la population de référence.
Louis Laurencelle
doaj +1 more source
Rémanence de Madame Bovary dans l’édition illustrée
Flaubert: Revue Critique et Génétique, 2014 This article focuses on the illustrated editions of Madame Bovary. After Flaubert’s death these editions were popular and multiplied until the end of the 1850’s. They represent a testimony of the novel’s reception by illustrators.
Bruno Gallice
doaj +1 more source
Book Review: Staging the French Revolution: Cultural Politics and the Paris Opera, 1789-1794 [PDF]
, 2013 Dr. Wayne Wentzel\u27s review of Mark Darlow, Staging the French Revolution: Cultural Politics and the Paris Opéra, 1789-1794. Oxford and New York: Oxford University Press, 2012. xi + 421 pp.
Wentzel, Wayne C.
core +1 more source