Results 71 to 80 of about 390,298 (260)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Illustrations and redescriptions of Simon’s little known salticid taxa from West-Africa (Araneae: Salticidae) [PDF]
Redescriptions and illustrations are given for following taxa: Hermotimus Simon, 1903 – type species H. coriaceus Simon, 1903 from West Africa, Longarenus Simon, 1903 – type species L.
Szüts, T.
doaj
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Le bestiaire médiévaliste comme produit dérivé
Devant le constat de la multiplication des bestiaires médiévalistes dérivant d’univers fictionnels préexistants (romans, films, jeux vidéo, séries), l’autrice s’intéresse à ce qui fait la séduction de ces bestiaires pour les lecteurs et à la manière dont
Maud Pérez-Simon
doaj +1 more source
Carroll e Tenniel: le immagini di Alice
The intent of this paper is to explore the importance of the images in Carroll’s work and the increase in meaning they bring to the written text. Therefore, some illustrations by Carroll in the manuscript Alice’s Adventures Under Ground and others by ...
Chiara Castellani
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Front matter, including a handwritten letter from C.F. Gore, and illustrations by George Cruikshank from volume I of Modern Chivalry.Preface signed: C. F. G. [i. e. Catherine Frances Gore] Title vignettes. Inserted: ALS. from Mrs.
Gore, Mrs. (Catherine Grace Frances), 1799-1861; Cruikshank, George, 1792-1878
core +1 more source
PROJECT “BULGARIAN LITERATURE FOR CHILDREN AND YOUTH XX–XXI C.”
The text presents the idea and the main directions of work of “Bulgarian Literature for Children and Adolescents of the 20th–21st Centuries” project, demonstrates its interdisciplinary nature, which combines literary, archival and psychodramatic ...
Alexandra Antonova
doaj +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source

