Results 141 to 150 of about 390,298 (260)

Eucalyptus terminalis F. Muell. [picture] /

open access: yes, 1900
Inscriptions: title below image, "F.P. Nodder pinxit 1778." -- lower left.; Plate 117 of Illustrations of the botany of Captain Cook's voyage round the world in H.M.S.

core  

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Illustrations of geometric tracery, from the paneling belonging to Carlisle Cathedral /

open access: yes
Plates published 1840-1842 by the author."G. Norman, Printer, Maiden Lane, Covent Garden."Plates engraved by John Saddler, G.B. Smith, and George Winter, after Robert William Billings.Mode of access: Internet.Library's copy bound with copy 2 of ...
Billings, Robert William, 1813-1874 architect.   +4 more
core  

Grevillea pteridifolia Knight [picture] /

open access: yes, 1900
Inscriptions: title below image, "J. F. Miller pinxit 1773." -- lower left.; Plate 261 of Illustrations of the botany of Captain Cook's voyage round the world in H.M.S. Endeavour in 1768-71 by Sir Joseph Banks and Daniel Solander ; with determinations by

core  

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Home - About - Disclaimer - Privacy