Results 81 to 90 of about 157,918 (296)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

MagicTalk: Implicit and explicit correlation learning for diffusion-based emotional talking face generation

Computational Visual Media
Generating emotional talking faces from a single portrait image remains a significant challenge. The simultaneous achievement of expressive emotional talking and accurate lip-sync is particularly difficult, as expressiveness is often compromised for lip ...
Chenxu Zhang, Chao Wang, Jianfeng Zhang, Hongyi Xu, Guoxian Song, You Xie, Linjie Luo, Yapeng Tian, Jiashi Feng, Xiaohu Guo   +9 more
doaj   +1 more source

Image-based modeling and rendering techniques : a survey

, 2023
A recente convergência entre computação gráfica e visão computacional levou à criação de um conjunto de técnicas denominadas modelagem e rendering baseados em imagens (MRBI). Modelagem baseada em imagens se refere ao processo de utilização de imagens para reconstrução de modelos geométricos 3D.
openaire   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Rapid Path Planning Algorithm for Percutaneous Rigid Needle Biopsy Based on Optical Illumination Principles

Sensors
Optimal needle trajectory selection is critical in biopsy procedures to minimize tissue damage and ensure diagnostic accuracy. Timely trajectory planning is essential, as it relies on preoperative CT imaging.
Jian Liu, Shuai Kang, Juan Ren, Dongxia Zhang, Bing Niu, Kai Xu   +5 more
doaj   +1 more source

Global Structure-From-Motion Enhanced Neural Radiance Fields 3D Reconstruction [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences
Urban three-dimensional modeling involves digitizing geographical elements such as urban ground and architecture, profoundly impacting urban management, planning, and development.
T. Ye, H. Huang, Y. Liu, J. Yang
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Overview of 3D Scene Viewpoints evaluation method

Virtual Reality & Intelligent Hardware, 2019
The research on 3D scene viewpoints has been a frontier problem in computer graphics and virtual reality technology. In a pioneering study, it had been extensively used in virtual scene understanding, image-based modeling, and visualization computing ...
Yan Zhang, Guangzheng Fei
doaj   +1 more source