Results 91 to 100 of about 12,109,327 (298)

Realizing the potential of magnetic resonance image guided radiotherapy in gynaecological and rectal cancer [PDF]

, 2019
CT-based radiotherapy workflow is limited by poor soft tissue definition in the pelvis and reliance on rigid registration methods. Current image-guided radiotherapy and adaptive radiotherapy models therefore have limited ability to improve clinical ...
Scurr, E, Brown, G, White, IM, Oelfke, U, Wetscherek, A, Scurr, Erica, Bhide, S, Sohaib, A, Bhide, Shreerang, Wetscherek, Andreas, Nill, S, Dearnaley, D, Lalondrelle, S, Brown, Gina, Oelfke, Uwe, Dearnaley, David, Lalondrelle, Susan, White, Ingrid M, Nill, Simeon, Sohaib, Aslam   +19 more
core   +1 more source

Tumor motion in lung cancers: An overview of four-dimensional radiotherapy treatment of lung cancers

Asian Journal of Oncology, 2017
Most modern radiotherapy centers have adopted contouring based treatment. Sparing of the normal structures has been made more achievable than ever before by use of technologies such as Intensity Modulated Radiotherapy (IMRT) and Image guided radiotherapy
Anusheel Munshi, Nilaxi Khataniar, Tharmar Ganesh   +2 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Guidelines and recommendations for radiologist staffing, education and training

Insights into Imaging
This article outlines the radiology-related staffing and education/training guidelines and recommendations developed by the European Commission-funded EU-REST (European Union Radiation, Education, Staffing & Training) project.
Adrian P. Brady, Christian Loewe, Boris Brkljacic, Graciano Paulo, Martina Szucsich, Monika Hierath, on behalf of the European Society of Radiology   +6 more
doaj   +1 more source

Image-guided radiation therapy using computed tomography in radiotherapy

, 2010
The sharp dose gradients in intensity-modulated radiation therapy increase the treatment sensitivity to various inter- and intra-fractional uncertainties, in which a slight anatomical change may greatly alter the actual dose delivered.
Vincent Wing Cheung Wu, Winky Wing Ki Fung   +1 more
core   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Image-guided radiation therapy: Physician′s perspectives

Journal of Medical Physics, 2012
The evolution of radiotherapy has been ontogenetically linked to medical imaging. Over the years, major technological innovations have resulted in substantial improvements in radiotherapy planning, delivery, and verification.
T Gupta, C Anand Narayan
doaj   +1 more source

Feasibility of image-guided radiotherapy based on tomotherapy for the treatment of locally advanced anal carcinoma

, 2011
The standard of care for locally advanced anal cancer has been concurrent chemoradiation. However, conventional treatment with 3-dimensional radiotherapy is associated with significant toxicity.
Vo, Richard P, Betz, Michael, Cohen, Deirdre, Mills, Melissa, Jang, Siyoung, Khan, Rihan, Nguyen, Nam P, Vinh-Hung, Vincent, Chi, Alexander, Sroka, Thomas, Ewell, Lars, Vock, Jacqueline   +11 more
core  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source