Results 211 to 220 of about 354,551 (319)

WDR5‐H3K4me3 Epigenetic Axis Promotes TRMT6‐Dependent tRNA M1A Modification to Facilitate Triple‐Negative Breast Cancer Progression by Suppressing Ferroptosis

Advanced Science, EarlyView.
Upregulated TRMT6 forms aberrant hypermethylation of a specific tRNA pool and serves as a predictor of poor prognosis in TNBC. This m1A modification in tRNAs enhances translation of FTH1 and FTL, reducing the pool of bioavailable Fe2⁺. Reduced Fe2+ availability impairs RSL3‐induced lipid peroxidation and tumor progression.
Yuqing Lei, Xue Wang, Jiahe Liu, Zixu Niu, Jiaqi Hua, Qian Guo, Dan Du, Yuanchang Zhu, Fucheng He, Mingxia Zhou, Hongle Li, Jing He, Jun Li   +12 more
wiley   +1 more source

Hypofractionated image-guided radiotherapy with 70 Gy in 28 fractions for prostate cancer confined to the pelvis: a single institute experience in Taiwan. [PDF]

BMC Urol
Mu HL, Chi MS, Ko HL, Juang GD, Hwang TI, Chi KH, Yang KL.   +6 more
europepmc   +1 more source

Evaluation of non-vendor magnetic resonance imaging sequences for use in bladder cancer magnetic resonance image guided radiotherapy. [PDF]

Phys Imaging Radiat Oncol, 2023
Chick J, Alexander S, Herbert T, Huddart R, Ingle M, Mitchell A, Nill S, Oelfke U, Dunlop A, Hafeez S.   +9 more
europepmc   +1 more source

Low YTHDC1 Expression Upregulates FSCN1 to Promote Nuclear F‐Actin Formation and Facilitate Double‐strand DNA Breaks Repair in TMZ‐Resistant Glioblastoma

Advanced Science, EarlyView.
This study revealed that low expression of YTHDC1 in TMZ‐resistant GBM cells leads to increased FSCN1 expression, which is suppressed by m6A modification. FSCN1 activates the CDC42/N‐WASP/Arp2/3 axis in the cell nucleus by recruiting the guanine nucleotide exchange factor (GEF) family member FGD1, thereby promoting F‐actin polymerization in the nucleus.
Minglong Yang, Wanxiang Niu, Yuanfei Wang, Peng Chen, Maolin Mu, Xiaoming Zhang, Ben Xu, Shanshan Hu, Chaoshi Niu, Pengfei Wu   +9 more
wiley   +1 more source

Treatment outcome of localized prostate cancer using transperineal ultrasound image-guided radiotherapy. [PDF]

Radiat Oncol
Takai K, Watanabe R, Hyogo KI, Ito Y, Minagawa N, Sato Y, Matsuda Y, Nemoto K.   +7 more
europepmc   +1 more source

Intra-prostatic gold fiducial marker insertion for image-guided radiotherapy (IGRT): five-year experience on 795 patients. [PDF]

BMC Med Imaging, 2023
Mahdavi A, Mofid B, Taghizadeh-Hesary F.
europepmc   +1 more source

The IMPORT HIGH Image-guided Radiotherapy Study: A Model for Assessing Image-guided Radiotherapy

Clinical Oncology, 2015
Donovan, E.M., Harris, E.J., Mukesh, M.B., Haviland, Joanne S., Titley, J., Griffin, C., Coles, C.E., Evans, P.M.   +7 more
openaire   +5 more sources

Irradiated Tumor Cell‐Derived Microparticles Activate Systemic Anti‐Tumor Immunity via the STING/NLRP3/GSDMD Axis in Neutrophils

Advanced Science, EarlyView.
Radiotherapy induces tumor cells to release microparticles (RT‐MPs) into the circulation. The mitochondrial DNA carried by these RT‐MPs activates the STING/NLRP3/GSDMD axis in splenic neutrophils, triggering IL‐1β secretion. This, in turn, enhances dendritic cell function and facilitates the formation of cytotoxic T lymphocytes, thereby promoting ...
Yan Hu, Jiacheng Wang, Mengjie Che, Zheng Yang, Jingshu Meng, Xiao Yang, Yue Deng, Zhiyuan Zhou, Yijun Wang, Wenwen Wei, Zhanjie Zhang, Bian Wu, You Qin, Kunyu Yang, Honglin Jin, Fang Huang, Yajie Sun, Lu Wen, Chao Wan   +18 more
wiley   +1 more source

Can Deep Learning-Based Auto-Contouring Software Achieve Accurate Pelvic Volume Delineation in Volumetric Image-Guided Radiotherapy for Prostate Cancer? A Preliminary Multicentric Analysis. [PDF]

Curr Oncol
Grossi C, Munoz F, Bonavero I, Ngassam EJT, Garibaldi E, Airaldi C, Celia E, Nassisi D, Brignoli A, Trino E, Bianco L, Leardi S, Bongiovanni D, Valero C, Redda MGR.   +14 more
europepmc   +1 more source

Three discipline collaborative radiation therapy (3DCRT) special debate: Equipment development is stifling innovation in radiation oncology [PDF]

, 2011
Kim, Leonard, Markovina, Stephanie, Van Nest, Samantha J, Eisaman, Subarna, Santanam, Lakshmi, Sullivan, Julie M, Dominello, Michael, Joiner, Michael C, Burmeister, Jay   +8 more
core   +1 more source