Results 91 to 100 of about 98,087,126 (282)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
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, 2017 This photograph originally appeared in the 2017 Research student photography and image competition held to celebrate National Science Week (18 August - 8 September 2017).
Azam Dolatshah
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IEEE AccessWith the remarkable progress in fire detection and segmentation models, it has become crucial to build more diverse labeled datasets to ensure efficient training.
Xuan Nghia Huynh, Jae Kyu Suhr
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Facial expression morphing: enhancing visual fidelity and preserving facial details in CycleGAN-based expression synthesis [PDF]
PeerJ Computer ScienceRecent advancements in facial expression synthesis using deep learning, particularly with Cycle-Consistent Adversarial Networks (CycleGAN), have led to impressive results.
Chayanon Sub-r-pa +2 more
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Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
MathematicsWhen objects are obscured by shadows or dim surroundings, image quality is improved by fusing near-infrared and visible-light images. At night, when visible and NIR lights are insufficient, long-wave infrared (LWIR) imaging can be utilized, necessitating
Dong-Min Son, Sung-Hak Lee
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
U-Sketch: Bridging the Gap for Efficient and Realistic Sketch-to-Image Synthesis
IEEE AccessDiffusion models have demonstrated remarkable performance in text-to-image synthesis, producing realistic, high-resolution images that faithfully adhere to the corresponding text-prompts. However, they still fall behind in sketch-to-image synthesis tasks,
Ilias Mitsouras +3 more
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Multi‐head mutual‐attention CycleGAN for unpaired image‐to‐image translation
IET Image Processing, 2020 The image‐to‐image translation, i.e. from source image domain to target image domain, has made significant progress in recent years. The most popular method for unpaired image‐to‐image translation is CycleGAN.
Wei Ji, Jing Guo, Yun Li
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source