Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Colour Doppler imaging of the orbital vasculature in Graves' disease with computed tomographic correlation [PDF]
Mohan Rao K N
openalex +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Pulse energy enhancement by means of fiber Bragg gratings in actively Q-switched Tm3+-doped fiber lasers operating at 2050 nm and 2090 nm [PDF]
Schneider Julian +6 more
doaj +1 more source
Faster R-CNN-Based Glomerular Detection in Multistained Human Whole Slide Images [PDF]
Yoshimasa Kawazoe +6 more
openalex +1 more source
Classification of Breast Cancer Ultrasound Images with Deep Learning-Based Models [PDF]
Fatih Uysal, Mehmet Murat Köse
openalex +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
High-peak-power Ho3+ and Tm3+-doped fiber MOPA for mid-IR conversion [PDF]
Lorenz Dominik +6 more
doaj +1 more source
Boosting Resolution and Recovering Texture of 2D and 3D Micro‐CT Images with Deep Learning [PDF]
Ying Da Wang +2 more
openalex +1 more source

