Results 131 to 140 of about 13,865,268 (312)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
File forensics for RAW camera image formats [PDF]
, 2012 Recent research in multimedia forensics has developed a variety of methods to detect image tampering and to identify the origin of image files. Many of these techniques are based on characteristics in the JPEG format, as it is the most used file format ...
Gloe, Thomas +2 more
core
Toward real-time margin assessment in breast-conserving surgery with hyperspectral imaging
Scientific ReportsMargin assessment in breast-conserving surgery (BSC) remains a critical challenge, with 20-25% of cases resulting in inadequate tumor resection, increasing the risk of local recurrence and the need for additional treatment. In this study, we evaluate the
Lynn-Jade S. Jong +9 more
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Revue Française de Photogrammétrie et de TélédétectionLe suivi à long terme de la productivité des prairies de montagne est crucial pour comprendre les réponses de ces écosystèmes au réchauffement climatique. Bien que les archives Landsat soient la référence pour ces analyses, leur fréquence temporelle (16
Pierre-Alexis Herrault +2 more
doaj
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Body Image in Australian adolescents: Exploring functional and aesthetic body image across the sporting context [PDF]
, 2012 This thesis take a multidimensional view on body image, suggesting that perceptions of the body are not restricted to the way the body “looks”; they may also extend to the way the body “functions”.
Abbott, Bree
core
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
MIRACLE at ImageCLEFannot 2008: Classification of Image Features for Medical Image Annotation [PDF]
, 2008 This paper describes the participation of MIRACLE research consortium at the ImageCLEF Medical Image Annotation task of ImageCLEF 2008. A lot of effort was invested this year to develop our own image analysis system, based on MATLAB, to be used in our ...
Villena Román, Julio +3 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source