Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Dr. Bob Burghardt of Veterinary Anatomy and Public Health is shown working in the Image Analysis Laboratory. Writing on the photo or group of photos: Dr. Bob Burghardt of Veterinary Anatomy and Public Health.
Rydzewski, Tony
core
DHAFGan: A dense hybrid attention fusion generative adversarial network for infrared and visible image fusion. [PDF]
Hong Q, Xu Z, Qin D, Zheng Y, Zhang H.
europepmc +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
De IMAGE 2.2 implementatie van de SRES scenario's
IMAGE is een geintegreerd ketenmodel dat wordt gebruikt voor mondiale assessments, met name betreffende klimaatverandering. De belangrijkste doelen van IMAGE zijn om bij te dragen aan het wetenschappelijke begrip van klimaatverandering en om de ...
Eickhout B, IMAGE team
core
MIPAR Spotlight: Shedding Light on Next-Generation Detection for Microscopists [PDF]
Nordqvist Sammy +3 more
doaj +1 more source
ECPD-MIE: An adaptive entropy-controlled chaotic permutation-diffusion scheme for secure multi-image encryption of grayscale and color images. [PDF]
Mishra BB, Patro KAK, Das S.
europepmc +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Microbially induced corrosion - fighting an invisible enemy..!
This photograph originally appeared in the 2014 Research student photography and image competition held to celebrate National Science Week (Aug 16-24).
Javed, Muhammad Awais +1 more
core

