Results 141 to 150 of about 10,895,923 (318)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

A generic postprocessing technique for image compression

open access: yes, 2001
A postprocessing approach is developed for image coding applications. In this approach, a distortion-recovery model extracts multi-resolution edge features from the decompressed image and uses these visual features as input to estimate the difference ...
He, Z., Luk, B. L., Chen, S.
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Toward real-time margin assessment in breast-conserving surgery with hyperspectral imaging

open access: yesScientific Reports
Margin assessment in breast-conserving surgery (BSC) remains a critical challenge, with 20-25% of cases resulting in inadequate tumor resection, increasing the risk of local recurrence and the need for additional treatment. In this study, we evaluate the
Lynn-Jade S. Jong   +9 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Enhanced image retrieval using spatial information and ontologies

open access: yes, 2012
New approaches are essential to improve the inference of semantic relationships from low-level features for image annotation and retrieval. Current research on image annotation sometimes represents images in terms of regions and objects, but pays little ...
Muda, Z.
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

A brief summary of digital image enhancement [PDF]

open access: yes
Digital image processing is a modern branch of computer application. With the help of computers the visual quality of original images which were blurred by external interferences or optical transfer function of transmission channel can be improved so ...
Qiang, Gu Yun
core  

Low bandwidth, image transmission amateur microsatellites [PDF]

open access: yes, 1993
Some recent amateur packet satellites carry open access digital store- and-forward transponders which implement common communication protocols known as PACSAT PROTOCOL SUITE.
Mwambela, A.J.
core  

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