Results 171 to 180 of about 13,444,099 (340)

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Photon-Counting Chest CT at Radiography-Comparable Dose Levels: Impact on Opportunistic Visual and Semiautomated Coronary Calcium Quantification. [PDF]

Invest Radiol
Kroschke J, Kerber B, Eberhard M, Ensle F, Frauenfelder T, Jungblut L.   +5 more
europepmc   +1 more source

Selecting Targets for Tumor Imaging: An Overview of Cancer-Associated Membrane Proteins [PDF]

, 2016
Martin C. Boonstra, Susanna W.L. de Geus, Hendrica A.J.M. Prevoo, Lukas J.A.C. Hawinkels, C.J.H. Van de Velde, Peter J.K. Kuppen, Alexander L. Vahrmeijer, Cornelis F.M. Sier   +7 more
openalex   +1 more source

Survey of single image super‐resolution reconstruction [PDF]

, 2020
Kai Li, Shenghao Yang, Runting Dong, Xiaoying Wang, Jianqiang Huang   +4 more
openalex   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

A convolutional neural network to classify American Sign Language fingerspelling from depth and colour images [PDF]

, 2017
Salem Ameen, Sunil Vadera
openalex   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Cover Image

Emergency, 2014
Cover Image
doaj  

Deep Learning HASTE for Upper Abdominal MRI: Improved Image Quality, Speed, and Energy Efficiency in a Prospective Study. [PDF]

NMR Biomed
Gotta J, Bachir AA, Gruenewald LD, Strecker R, Nickel D, Martin SS, Booz C, Mahmoudi S, Al-Saleh S, Dahm D, Konrad P, Bernatz S, Reschke P, Höhne E, Hammerstingl RM, Eichler K, Gruber-Rouh T, Haberkorn SM, D'Angelo T, Weber C, Zeuzem S, Wiegering A, Sinkus R, Vogl TJ, Koch V.   +24 more
europepmc   +1 more source

Precise synthesis of unique polydopamine/mesoporous calcium phosphate hollow Janus nanoparticles for imaging-guided chemo-photothermal synergistic therapy

, 2017
Manjie Zhang, Lingyu Zhang, Yidan Chen, Lu Li, Zhong‐Min Su, Chungang Wang   +5 more
openalex   +2 more sources