Results 141 to 150 of about 926,300 (280)

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

IntegrAlign: a comprehensive tool for multi-immunofluorescence panel integration through image alignment. [PDF]

Bioinformatics
Hermet L, Laoubi L, Scavino M, Doffin AC, Gazeu A, Berthet J, Pillat B, Tissot S, Rusakiewicz S, Michallet MC, Bendriss-Vermare N, Valladeau-Guilemond J, Hausser J, Caux C, Hubert M.   +14 more
europepmc   +1 more source

RAW Bayer Domain Image Alignment

, 2022
Every day millions of photographs are captured with handheld mobile devices. Depending on the capturing conditions, multiple images may be captured in order to obtain more information on the scene in question. These multiple images are captured sequentially and called raw images. As a result, depending on the scene dynamics and due to the camera shake (
openaire   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Automatic ultrasound image alignment for diagnosis of pediatric distal forearm fractures. [PDF]

Int J Comput Assist Radiol Surg
Liu P, Hu Y, Schultz J, Xu J, von Schrottenberg C, Schwerk P, Pohl J, Fitze G, Speidel S, Pfeiffer M.   +9 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Robust Cylindrical Panorama Stitching for Low-Texture Scenes Based on Image Alignment Using Deep Learning and Iterative Optimization. [PDF]

Sensors (Basel), 2019
Kang L, Wei Y, Jiang J, Xie Y.
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

An Infrared and Visible Image Alignment Method Based on Gradient Distribution Properties and Scale-Invariant Features in Electric Power Scenes. [PDF]

J Imaging
Zhu L, Mao Y, Chen C, Ning L.
europepmc   +1 more source