Results 161 to 170 of about 34,558,744 (307)

Fundus image analysis of retinitis pigmentosa using artificial intelligence. [PDF]

PLoS One
Ubukata S, Masayoshi K, Katada Y, Yang L, Ozawa N, Ibuki M, Negishi K, Kurihara T.   +7 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Artificial Intelligence in Burn and Wound Care: Image Analysis, Prediction, and Clinical Integration. [PDF]

J Burn Care Res
Khorsandi J, Mirharooni J, Kahen J, Tariq E, Harouni M, Franzoni D, MacDavid J.   +6 more
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Anterior Segment Measurement Dataset Using Ultrasound Biomicroscopy Image Analysis. [PDF]

Transl Vis Sci Technol
Kolosky T, Forbes HE, Levin MR, Martinez C, Madigan WP, Alexander JL.   +5 more
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Early identification of glufosinate-resistant soybeans using plant image analysis. [PDF]

Front Plant Sci
Yook MJ, Chang BK, Noh TK, Kim DS.
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Advanced Imaging of Biochemical Recurrent Prostate Cancer With PET, MRI, and Radiomics

Frontiers in Oncology, 2020
Faiq Shaikh, Diana Dupont-Roettger, Jamshid Dehmeshki, Jamshid Dehmeshki, Olga Kubassova, Mohammed I. Quraishi   +5 more
doaj   +1 more source

A deep learning framework for efficient pathology image analysis. [PDF]

Nat Commun
Neidlinger P, Lenz T, Foersch S, Loeffler CML, Clusmann J, Gustav M, Shaktah LA, Langer R, Dislich B, Boardman LA, French AJ, Goode EL, Gsur A, Brezina S, Gunter MJ, Steinfelder R, Behrens HM, Röcken C, Harrison T, Peters U, Phipps AI, Curigliano G, Fusco N, Marra A, Hoffmeister M, Brenner H, Kather JN.   +26 more
europepmc   +1 more source