Results 141 to 150 of about 317,725 (334)
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Technical note: The effect of image annotation with minimal manual interaction for semiautomatic prostate segmentation in CT images using fully convolutional neural networks. [PDF]
Shahedi M, Dormer JD, Halicek M, Fei B.
europepmc +1 more source
Automatic Image Annotation using Visual Content and Folksonomies
Roland Mörzinger +3 more
openalex +1 more source
Image Annotation Support through Databases and Editing Systems
Yuzo Marukawa
openalex +2 more sources
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
The cast thin sections of tight oil reservoirs contain important parameters such as rock mineral composition and content, porosity, permeability and stratigraphic characteristics, which are of great significance for reservoir evaluation.
Tao Liu +9 more
doaj +1 more source
YOLO-ODD: an improved YOLOv8s model for onion foliar disease detection
Onion crops are affected by many diseases at different stages of growth, resulting in significant yield loss. The early detection of diseases helps in the timely incorporation of management practices, thereby reducing yield losses.
Anusha Raj +9 more
doaj +1 more source

