Results 151 to 160 of about 317,725 (334)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

(ExMod) Model for Medical Image Segmentation Using Scribble Annotations [PDF]

Hateef Alshewaier, Yipeng Qin, Xianfang Sun   +2 more
openalex   +1 more source

VANO: a volume-object image annotation system [PDF]

, 2009
Hanchuan Peng, Fuhui Long, Eugene W. Myers   +2 more
openalex   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

AI-enabled radiologist in the loop: novel AI-based framework to augment radiologist performance for COVID-19 chest CT medical image annotation and classification from pneumonia. [PDF]

Neural Comput Appl, 2023
Ghayvat H, Awais M, Bashir AK, Pandya S, Zuhair M, Rashid M, Nebhen J.   +6 more
europepmc   +1 more source

AISO: Annotation of Image Segments with Ontologies [PDF]

, 2014
Nikhil Tej Lingutla, Justin Preece, Siniša Todorović, Laurel Cooper, Laura Moore, Pankaj Jaiswal   +5 more
openalex   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Automated annotation of gene expression image sequences via non-parametric factor analysis and conditional random fields [PDF]

, 2013
Iulian Pruteanu-Malinici, William H. Majoros, Uwe Ohler   +2 more
openalex   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

An Adaptive Low-Rank Modeling-Based Active Learning Method for Medical Image Annotation. [PDF]

Ing Rech Biomed, 2021
He S, Wu J, Lian C, Gach HM, Mutic S, Bosch W, Michalski J, Li H.   +7 more
europepmc   +1 more source