Results 71 to 80 of about 2,018,951 (327)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

A Self-Organizing System for Classifying Complex Images: Natural Textures and Synthetic Aperture Radar [PDF]

open access: yes, 1996
A self-organizing architecture is developed for image region classification. The system consists of a preprocessor that utilizes multi-scale filtering, competition, cooperation, and diffusion to compute a vector of image boundary and surface properties ...
Grossberg, Stephen, Williamson, James
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Automated grading of mangoes based on surface defect detection using a combined approach of image segmentation

open access: yesEnvironment Conservation Journal, 2020
Image segmentation is an essential and critical step in huge number of applications of image processing. Accuracy of image segmentation influence retrieved information for further processing in classification and other task.
Neeraj Kumari   +3 more
doaj   +1 more source

Classification images: A review

open access: yesJournal of Vision, 2011
Classification images have recently become a widely used tool in visual psychophysics. Here, I review the development of classification image methods over the past fifteen years. I provide some historical background, describing how classification images and related methods grew out of established statistical and mathematical frameworks and became ...
openaire   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Images Classification Paramo

open access: yes, 2022
El Páramo, los páramos andinos, juega un papel importante en nuestros ecosistemas ya que equilibran los recursos hídricos y pueden retener cantidades sustanciales de carbono.Esta investigación se realizó en la provincia de Tungurahua, específicamente en el distrito de Quero, siendo esta la región más importante del Páramo ecuatoriano.
CASTELO, MARCO   +2 more
openaire   +1 more source

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