Results 211 to 220 of about 285,255 (319)

Engineered Chitosan‐Derived Nanocarrier for Efficient siRNA Delivery to Peripheral and Central Neurons

Advanced Healthcare Materials, EarlyView.
This study introduces a novel chitosan‐based nanocarrier functionalized with a neurotropic protein for efficient siRNA delivery to neurons. The polyplexes demonstrate enhanced neuronal binding, retrograde transport, and PTEN silencing, promoting axonal outgrowth.
Ana P. Spencer, Adriana Vilaça, Miguel Xavier, Rafael Santos, Ariel Ionescu, María Lázaro, Victoria Leiro, Eran Perlson, Sofia C. Guimarães, Ben M. Maoz, Ana P. Pêgo   +10 more
wiley   +1 more source

Detection of Cervical Cancer and High Grade Neoplastic Lesions by a Combination of Liquid‐Based Sampling Preparation and DNA Measurements Using Automated Image Cytometry

, 2005
Xiao Rong Sun, Jian Wang, David M. Garner, Branko Palcic   +3 more
openalex   +1 more source

Advanced Multipurpose Spectroscopic Nanobio‐Device for Concurrent Lab‐on‐a‐Chip Label‐Free Separation and Detection of Extracellular Vesicles as Key‐Biomarkers for Point‐of‐Care Cardiovascular Disease Diagnostics

Advanced Healthcare Materials, EarlyView.
AIMSPec‐LoC is a novel lab‐on‐a‐chip platform integrating size‐based extracellular vesicle (EVs) separation with label‐free Raman spectroscopy and AI‐powered classification via SKiNET. This high‐throughput, portable system enables real‐time, multiplexed molecular fingerprinting of EVs from biofluids, offering transformative potential for early, non ...
Emma Buchan, Jonathan James Stanley Rickard, Mark Robert Thomas, Pola Goldberg Oppenheimer   +3 more
wiley   +1 more source

Value of automatic DNA image cytometry for diagnosing lung cancer. [PDF]

Oncol Lett, 2018
Shi A, Min W, Xiang L, Xu W, Jiang T.
europepmc   +1 more source

Carbon‐Based Flexible Electrode for Efficient Electrochemical Generation of Reactive Chlorine Species in Tumor Therapy

Advanced Healthcare Materials, EarlyView.
A flexible electrode loaded with a carbon nanowire network (CC@C‐NWN) is developed for electrochemically generating reactive chlorine species (RCS) from abundant chloride ions in body fluids for tumor therapy. CC@C‐NWN enhances chlorine evolution, inducing redox dysregulation and synergistic apoptosis‐ferroptosis in tumor cells.
Cuinan Jiang, Zhaoyu Chen, Ruihao Yang, Ziga Luogu, Qian Ren, Hao Hu, Kaixin Wang, Senlin Li, Changlin Deng, Meng Li, Lu Zheng   +10 more
wiley   +1 more source

Quantification of the rat spinal microglial response to peripheral nerve injury as revealed by immunohistochemical image analysis and flow cytometry

, 2007
J. Blackbeard, Kieran P. O’Dea, V.C.J. Wallace, Andrew R. Segerdahl, T. Pheby, Masao Takata, Mark J. Field, Andrew S.C. Rice   +7 more
openalex   +1 more source

High throughput measurement of Ca2+ dynamics for drug risk assessment in human stem cell-derived cardiomyocytes by kinetic image cytometry [PDF]

, 2012
Fabio Cerignoli, David Charlot, Ross Whittaker, Randy Ingermanson, Piyush Gehalot, A. K. Savchenko, David J. Gallacher, Rob Towart, Jeffrey H. Price, Patrick M. McDonough, Mark Mercola   +10 more
openalex   +1 more source

A high-throughput inhibition assay to study MERS-CoV antibody interactions using image cytometry. [PDF]

J Virol Methods, 2019
Rosen O, Chan LL, Abiona OM, Gough P, Wang L, Shi W, Zhang Y, Wang N, Kong WP, McLellan JS, Graham BS, Corbett KS.   +11 more
europepmc   +1 more source

RBC Membrane‐Camouflaged Nanosystem‐Mediated Synergistic Drug Combination for Enhanced Anti‐Tumor Therapy

Advanced Healthcare Materials, EarlyView.
An RBC membrane camouflaged, cell‐penetrating peptides R8‐based drug delivery system is constructed to achieve a synergistic combination of natural compounds triptolide (TP) and celastrol (Cel), inducing tumor cell apoptosis, reducing tumor metastasis invasion and triggering autophagy disorder in breast cancer and liver cancer.
Qian Cheng, Xuemei Zhong, Lu Deng, Xinling He, Miaoxizi Luo, Ruibing Wang, Jinming Zhang   +6 more
wiley   +1 more source

Prognostic Impact of DNA-Image-Cytometry in Neuroendocrine (Carcinoid) Tumours

Cellular Oncology, 2006
I. Petersen
doaj   +2 more sources