Results 141 to 150 of about 1,341,334 (344)

NanoCMSer: a consensus molecular subtype stratification tool for fresh‐frozen and paraffin‐embedded colorectal cancer samples

open access: yesMolecular Oncology, EarlyView.
Consensus molecular subtypes (CMS1‐4) have been identified to study colorectal cancer heterogeneity and serve as potential biomarkers. In this study, we developed and evaluated NanoCMSer, a NanoString‐based classifier using 55 genes, optimized for FF and FFPE to facilitate the clinical evaluation of CMS subtyping.
Arezo Torang   +10 more
wiley   +1 more source

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

open access: yesMolecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad   +13 more
wiley   +1 more source

A Block Based Scheme for Enhancing Low Luminated Images [PDF]

open access: yesInternational Journal of Multimedia & Its Applications(IJMA), Vol.2, No.3, August 2010, 2010
In this paper the background detection in images in poor lighting can be done by the use of morphological filters. Lately contrast image enhancement technique is used to detect the background in image which uses Weber's Law. The proposed technique is more effective one in which the background detection in image can be done in color images.
arxiv  

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

open access: yesMolecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran   +16 more
wiley   +1 more source

Robust acute myeloid leukemia engraftment in humanized scaffolds using injectable biomaterials and intravenous xenotransplantation

open access: yesMolecular Oncology, EarlyView.
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa   +13 more
wiley   +1 more source

A mine image enhancement method based on structural texture decomposition

open access: yesGong-kuang zidonghua
There is a phenomenon of low lighting and excessive dust in underground mines, which leads to uneven lighting, blurriness, and loss of details in the images captured by monitoring videos. It affects subsequent intelligent image recognition. Existing mine
ZHANG Hong, SUO Tingfeng, SONG Wanying
doaj   +1 more source

Physics-Inspired Synthesized Underwater Image Dataset [PDF]

open access: yesarXiv
This paper introduces the physics-inspired synthesized underwater image dataset (PHISWID), a dataset tailored for enhancing underwater image processing through physics-inspired image synthesis. For underwater image enhancement, data-driven approaches (e.g., deep neural networks) typically demand extensive datasets, yet acquiring paired clean and ...
arxiv  

Obstructive nephropathy: evaluation with dynamic Gd-DTPA-enhanced MR imaging. [PDF]

open access: green, 1990
Richard C. Semelka   +4 more
openalex   +1 more source

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu   +7 more
wiley   +1 more source

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