Results 171 to 180 of about 1,341,334 (344)

Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance

open access: yesMolecular Oncology, EarlyView.
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren   +4 more
wiley   +1 more source

Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma

open access: yesMolecular Oncology, EarlyView.
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh   +6 more
wiley   +1 more source

A joint image super‐resolution network for multiple degradations removal via complementary transformer and convolutional neural network

open access: yesIET Image Processing
While recent years have witnessed the unprecedented success of deep convolutional neural networks (CNNs) and vision transformers in single‐image super‐resolution (SISR), the degradation assumptions are simple and usually bicubic downsampling. Thus, their
Guoping Li, Zhenting Zhou, Guozhong Wang
doaj   +1 more source

Recognition-Oriented Low-Light Image Enhancement based on Global and Pixelwise Optimization [PDF]

open access: yesarXiv
In this paper, we propose a novel low-light image enhancement method aimed at improving the performance of recognition models. Despite recent advances in deep learning, the recognition of images under low-light conditions remains a challenge. Although existing low-light image enhancement methods have been developed to improve image visibility for human
arxiv  

Using helical CT to evaluate renal cell carcinoma in patients undergoing hemodialysis: value of early enhanced images. [PDF]

open access: bronze, 1999
S Takebayashi   +5 more
openalex   +1 more source

CircCCNB1 inhibits vasculogenic mimicry by sequestering NF90 to promote miR‐15b‐5p and miR‐7‐1‐3p processing in nasopharyngeal carcinoma

open access: yesMolecular Oncology, EarlyView.
CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan   +6 more
wiley   +1 more source

The Retinex enhancement algorithm for low‐light intensity image based on improved illumination map

open access: yesIET Image Processing
Taken in low‐light intensity conditions, image with low brightness affects processing precision. In this article, the Gamma Function based on the brightness average and weighted fusion method according to gray entropy is proposed, which is combined with ...
Ruidi Weng   +4 more
doaj   +1 more source

Image Enhancement Method for Binarization of Drawings

open access: bronze, 1988
Naonori Ueda   +3 more
openalex   +2 more sources

Enhancing images of facial expressions [PDF]

open access: bronze, 1999
Phil Benson   +4 more
openalex   +1 more source

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