Results 101 to 110 of about 12,417,327 (306)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
IEEE Access, 2017 Image fusion is a well-recognized and a conventional field of image processing. Image fusion provides an efficient way of enhancing and combining pixel-level data resulting in highly informative data for human perception as compared with individual input
Ayush Dogra, Bhawna Goyal, Sunil Agrawal
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Workshop at Data and Planning Center of NIFS in 2003 "Assesment of Fusion R&D" - The Critical Issues of Demonstration Fusion Reactor - [PDF]
, 2004 実証炉を構想しそれに至る課題を整理することは、核融合研究開発の現状を評価するうえで最も適切な作業のひとつと考えた。磁場閉じ込めと慣性閉じ込め核融合に共通な課題は経済性の改善である。また、磁場閉じ込めではトカマクもヘリカルも将来性のあるダイバータの開発は共通である。 経済性に関しては先進トカマクや高速点火方式のレーザ慣性核融合の提案が出てきている。さらにダイバータに関しては可動型や外置き型の研究が進められている。これらの要約は添付した。In order to asses the fusion ...
TAZIMA, Teruhiko +2 more
core
Quality assessment by region in spot images fused by means dual-tree complex wavelet transform [PDF]
, 2011 This work is motivated in providing and evaluating a fusion algorithm of remotely sensed images, i.e. the fusion of a high spatial resolution panchromatic image with a multi-spectral image (also known as pansharpening) using the dual-tree complex wavelet
Arquero Hidalgo, Águeda +2 more
core +1 more source
Critical Review of Multi-focus Image Fusion Based on Deep Learning Method [PDF]
Jisuanji kexue yu tansuoMulti-focus image fusion is an effective image fusion technology, which aims to combine source images from different focal planes of the same scene to obtain a good fusion result.
LI Ziqi, SU Yuxuan, SUN Jun, ZHANG Yonghong, XIA Qingfeng, YIN Hefeng
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Hyperspectral Image Resolution Enhancement Based on Spectral Unmixing and Information Fusion [PDF]
, 2011 Hyperspectral imaging sensors exibit high spectral resolution, but normally low spatial resolution. This leads to spectral signatures of pixels originating from different object types. Such pixels are called mixed pixels.
Avbelj, Janja +4 more
core
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source