Results 111 to 120 of about 12,653,288 (308)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Multi-sensor data fusion for urban area classification [PDF]
, 2011 Nowadays many sensors for information acquisition are widely employed in remote sensing and different properties of the objects can be revealed. Unfortunately each imaging sensor has its own limits on scene recognition in the sense of thematic, temporal,
Palubinskas, Gintautas +5 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Hyperspectral Image Resolution Enhancement Based on Spectral Unmixing and Information Fusion [PDF]
, 2011 Hyperspectral imaging sensors exibit high spectral resolution, but normally low spatial resolution. This leads to spectral signatures of pixels originating from different object types. Such pixels are called mixed pixels.
Avbelj, Janja +4 more
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
New Advances in Image Fusion [PDF]
, 2013 Image Fusion is an important branch of information fusion, and it is also an important technology for image understanding and computer vision. The fusion process is to merging different images into one to get more accurate description for the scene.
core +1 more source
User tracking using a wearable camera [PDF]
, 2012 —This paper addresses automatic indoor user tracking based on fusion of WLAN and image sensing. Our motivation is the increasing prevalence of wearable cameras, some of which can also capture WLAN data.
O'Connor, Noel E. +3 more
core +2 more sources
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Survey of Multi-sensor Image Fusion
, 2014 The paper presents multi-sensor image fusion and its relevant framework and technical characteristics. The image fusion is divided into three level fusions: pixel level, feature level and decision level.
Aolei Yang +8 more
core +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source