Results 111 to 120 of about 2,393,011 (281)
Frontiers in MedicineDiffusion models, a class of deep learning models based on probabilistic generative processes, progressively transform data into noise and then reconstruct the original data through an inverse process.
Yan Liu +6 more
doaj +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Generative Artificial Intelligence as a Catalyst for Change in Higher Education Art Study Programs
ComputersGenerative Artificial Intelligence (AI) has emerged as a transformative tool in art education, offering innovative avenues for creativity and learning. However, concerns persist among educators regarding the potential misuse of text-to-image generators ...
Anna Ansone +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
IEEE AccessThe fashion industry is constantly undergoing notable transformations fueled by advancements in technology, particularly AI and ML. This shift is driven by the desire for personalized clothing recommendations, especially among young females, who seek ...
Nethmi Pathirana +4 more
doaj +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
The Butterfly Effect: Color-Guided Image Generation From Unconditional Diffusion Models
IEEE AccessDiffusion models, which generate images by denoising initial noise through iterative steps, have emerged as a new state-of-the-art family of deep generative models.
Yunha Yeo, Daeho Um
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Knit-FLUX: Simulation of Knitted Fabric Images Based on Low-Rank Adaptation of Diffusion Models
Applied SciencesGenerative model-assisted design has become a trend, providing a new paradigm for knitted fabric image generation. The FLUX diffusion model was chosen to generate images in this study and was compared to other generative models.
Xiaochen Liu +4 more
doaj +1 more source