Results 101 to 110 of about 65,660 (274)

Knowledge Transfer in Semi-automatic Image Interpretation [PDF]

, 2015
Semi-automatic image interpretation systems utilize interactions between users and computers to adapt and update interpretation algorithms. We have studied the influence of human inputs on image interpretation by examining several knowledge transfer ...
Zhou, Jun, Caelli, Terry, Cheng, Li, Bischof, Walter F.   +3 more
core  

COMPUTER ASSISTED SYSTEM FOR FEATURES DETERMINATION OF LUNG NODULE FROM CHEST X RAY IMAGE [PDF]

, 2021
The Computer based / assisted system is proposed in this paper for feature extraction of lung nodule from the simple chest X-ray image. In recent years, the image processing mechanisms are widely used in several medical areas for early detection and in ...
DR. NITIN S. LINGAYAT, MANOJ R. TARAMBALE   +1 more
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Interactive Segmentation By Image Foresting Transform On Superpixel Graphs [PDF]

, 2015
There are many scenarios in which user interaction is essential for effective image segmentation. In this paper, we present a new interactive segmentation method based on the Image Foresting Transform (IFT).
Falcao A.X., Rauber P.E., Spina T.V., De Rezende P.J.   +3 more
core   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

An assessment model and implementation of stereo image quality [PDF]

, 2006
In the past decade, many display hardware manufacturers have initiated research into the construction of stereo display devices. Currently, the use of such displays is limited to the computer-aided design; research, military and medical applications ...
Raincock, Samantha
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Deep Learning-Based Semantic Segmentation and Classification of Otoscopic Images for Otitis Media Diagnosis and Health Promotion

Diagnostics
Background/Objectives: Otitis media (OM), including acute otitis media (AOM) and chronic otitis media (COM), is a common middle ear disease that can lead to significant morbidity if not accurately diagnosed.
Chien-Yi Yang, Che-Jui Lee, Wen-Sen Lai, Kuan-Yu Chen, Chung-Feng Kuo, Chieh Hsing Liu, Shao-Cheng Liu   +6 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Computer-Assisted Diagnosis for the Interpretation of Bone Scintigraphy. A new approach to improve diagnostic accuracy. [PDF]

, 2009
The most common cancers in the western countries are breast cancer in women and prostate cancer in men, and these cancer types, together with lung cancer, often metastasise to the skeleton.
Sadik, May
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