Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
National quality assurance program using digital cytopathology: a 5-year digital transformation experience by the Korean Society for Cytopathology [PDF]
Background Digital cytopathology (DC) is emerging as a transformative approach in quality assurance programs (QAP), though its comprehensive evaluation remains limited.
Yosep Chong +12 more
doaj +1 more source
Evaluation of ERTS-1 data for inventory of forest and rangeland and detection of forest stress [PDF]
The author has identified the following significant results. Results of photointerpretation indicated that ERTS is a good classifier of forest and nonforest lands (90 to 95 percent accurate).
Aldrich, R. C. +4 more
core +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Development and application of operational techniques for the inventory and monitoring of resources and uses for the Texas coastal zone. Volume 2: Appendices [PDF]
There are no author-identified significant results in this ...
Finley, R. +4 more
core +1 more source
Soliton Dynamics in Computational Anatomy
Computational anatomy (CA) has introduced the idea of anatomical structures being transformed by geodesic deformations on groups of diffeomorphisms. Among these geometric structures, landmarks and image outlines in CA are shown to be singular solutions ...
Alain Trouvé +59 more
core +2 more sources
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Artificial intelligence in ultrasound-guided regional anesthesia: bridging the gap between potential and practice: a narrative review [PDF]
Ultrasound-guided regional anesthesia (UGRA) offers substantial benefits in perioperative pain management; however, it remains underutilized because of technical complexity and training demands.
Yumin Jo +5 more
doaj +1 more source

