Results 71 to 80 of about 64,980 (226)
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Image interpretation using Bayesian networks
, 1996 oai:dsapce.library.iitb.ac.in:10054/8145The problem of image interpretation is one of inference with the help of domain knowledge. In this correspondence, we formulate the problem as the maximum a posteriori (MAP) estimate of a properly defined ...
KUMAR, VP, DESAI, UB
core +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Knowledge Transfer in Semi-automatic Image Interpretation
, 2015 Semi-automatic image interpretation systems utilize interactions between users and computers to adapt and update interpretation algorithms. We have studied the influence of human inputs on image interpretation by examining several knowledge transfer ...
Zhou, Jun +3 more
core
COMPUTER ASSISTED SYSTEM FOR FEATURES DETERMINATION OF LUNG NODULE FROM CHEST X RAY IMAGE
, 2021 The Computer based / assisted system is proposed in this paper for feature extraction of lung nodule from the simple chest X-ray image. In recent years, the image processing mechanisms are widely used in several medical areas for early detection and in ...
DR. NITIN S. LINGAYAT +1 more
core
FEBS Open Bio, EarlyView.KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
wiley +1 more source
FEBS Open Bio, EarlyView.In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara +3 more
wiley +1 more source
Interactive Segmentation By Image Foresting Transform On Superpixel Graphs
, 2015 There are many scenarios in which user interaction is essential for effective image segmentation. In this paper, we present a new interactive segmentation method based on the Image Foresting Transform (IFT).
Falcao A.X. +3 more
core +1 more source