Results 51 to 60 of about 15,646,431 (257)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Utilizing Smart Objects, Smart Filters, and Layers for Nondestructive Radiology Image Editing

MedEdPORTAL, 2010
The latest versions of Photoshop have introduced powerful and useful tools to radiologists. By using the program's Smart Objects, Smart Filters, and Layers, we can now preserve the original quality of our images and perform nondestructive, reversible ...
Mahesh Thapa, George Taylor
doaj   +1 more source

One-Shot Federated Learning on Medical Data Using Knowledge Distillation with Image Synthesis and Client Model Adaptation

, 2023
One-shot federated learning (FL) has emerged as a promising solution in scenarios where multiple communication rounds are not practical. Notably, as feature distributions in medical data are less discriminative than those of natural images, robust global
Jin, Kyong Hwan, Kim, Soopil, Adeli, Ehsan, Kang, Myeongkyun, Pohl, Kilian M., Park, Sang Hyun, Chikontwe, Philip   +6 more
core   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Evaluating diagnostic accuracy of large language models in neuroradiology cases using image inputs from JAMA neurology and JAMA clinical challenges

Scientific Reports
This study assesses the diagnostic performance of six LLMs —GPT-4v, GPT-4o, Gemini 1.5 Pro, Gemini 1.5 Flash, Claude 3.0, and Claude 3.5—on complex neurology cases from JAMA Neurology and JAMA, focusing on their image interpretation abilities.
Ahmed Albaqshi, Ji Su Ko, Chong Hyun Suh, Pae Sun Suh, Woo Hyun Shim, Hwon Heo, Chang-Yun Woo, Hyungjun Park   +7 more
doaj   +1 more source

Correlation of Semi-Quantitative Breast-Specific Gamma Imaging Findings with Dynamic Contrast-Enhanced MRI Parameters Assessed by a Computer-Aided Evaluation Program for Breast Cancer

대한영상의학회지, 2018
Purpose: To investigate whether a correlation exists between the semi-quantitative breast-specific gamma imaging (BSGI) findings and dynamic contrast-enhanced (DCE) MRI parameters assessed by a computer-aided evaluation program. Materials and Methods:
Saemee Ahn, Hye Ryoung Koo, Jeong Seon Park, Juhee Moon, Yun Young Choi, Min Sung Chung   +5 more
doaj   +1 more source

Information processing in computer-assisted interventions: 4th international conference, 2013 [PDF]

, 2014
Information processing in computer-assisted interventions: 4th international conference ...
Barratt, Dean, Jannin, Pierre, Fichtinger, Gabor, Cotin, Stéphane, Pierre Jannin, Jannin, P, Dean Barratt, Barratt, D, Fichtinger, G, Gabor Fichtinger, Cotin, S, Stephane Cotin   +11 more
core   +1 more source