Results 61 to 70 of about 287,120 (245)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana, Mariana Maschietto, Daniela Paz Leal, Ricardo de Santos de Oliveira, Mayara Ferreira Euzébio, Antonio Carlos dos Santos, Luciano Neder, Carlos Alberto Scrideli, Elvis Terci Valera   +8 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Development and application of operational techniques for the inventory and monitoring of resources and uses for the Texas coastal zone [PDF]

The author has identified the following significant results. Four LANDSAT scenes were analyzed for the Harbor Island area test sites to produce land cover and land use maps using both image interpretation and computer-assisted techniques.
Finley, R., Harwood, P., Hupp, B., Malin, P., Mcculloch, S., Murphy, D., Schell, J. A.   +6 more
core   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Computer-Assisted Aircraft Anti-Icing Fluids Endurance Time Determination

Aerospace, 2020
Deicing and anti-icing the aircraft using proper chemical fluids, prior takeoff, are mandatory. A thin layer of ice or snow can compromise the safety, causing lift loss and drag increase.
David Gagnon, Jean-Denis Brassard, Hassan Ezzaidi, Christophe Volat   +3 more
doaj   +1 more source

Development and application of operational techniques for the inventory and monitoring of resources and uses for the Texas coastal zone. Volume 1: Text [PDF]

The author has identified the following significant results. Image interpretation and computer-assisted techniques were developed to analyze LANDSAT scenes in support of resource inventory and monitoring requirements for the Texas coastal region.
Finley, R., Harwood, P., Malin, P. A., Mcculloch, S., Schell, J. A.   +4 more
core   +1 more source

ECG Wave-Maven: An Internet-based Electrocardiography Self-Assessment Program for Students and Clinicians [PDF]

, 2003
Purpose: To create a multimedia internet-based ECG teaching tool, with the ability to rapidly incorporate new clinical cases. Method: We created ECG Wave-Maven (http://ecg.bidmc.harvard.edu), a novel teaching tool with a direct link to an institution ...
Goldberger MD, Ary L., McClennen MD, Seth, Nathanson MD, Larry A., Safran MD, Charles   +3 more
core  

TernaryNet: Faster Deep Model Inference without GPUs for Medical 3D Segmentation using Sparse and Binary Convolutions

, 2018
Deep convolutional neural networks (DCNN) are currently ubiquitous in medical imaging. While their versatility and high quality results for common image analysis tasks including segmentation, localisation and prediction is astonishing, the large ...
Blendowski, Max, Heinrich, Mattias P., Oktay, Ozan   +2 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source