Results 111 to 120 of about 13,295,115 (295)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

SAREval: A Multi-Dimensional and Multi-Task Benchmark for Evaluating Visual Language Models on SAR Image Understanding

Remote Sensing
Vision-Language Models (VLMs) demonstrate significant potential for remote sensing interpretation through multimodal fusion and semantic representation of imagery.
Ziyan Wang, Lei Liu, Gang Wan, Yuchen Lu, Fengjie Zheng, Guangde Sun, Yixiang Huang, Shihao Guo, Xinyi Li, Liang Yuan   +9 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Image interpretation: exploiting multiple cues

, 2020
Multiple cues play a crucial role in image interpretation. A vision system that combines shape, colour, motion, prior scene knowledge and object motion behaviour is described.
Matas, J, Bober, M, Nguyen, L, Kittler, J   +3 more
core  

Detecting changes between a DSM and a high resolution SAR image with the support of simulation based separation of urban scenes [PDF]

, 2012
As a SAR image is often the only available data in crisis situations, e.g. after an earthquake, a change analysis of the SAR image with previously acquired data may enable a fast analysis of the damage caused by the disas-ter.
Reinartz, Peter, Auer, Stefan, Tao, Junyi   +2 more
core  

ePortfolios: Enhancing confidence in student radiographers' communication of radiographic anatomy and pathology. A cross‐sectional study

Journal of Medical Radiation Sciences
Introduction In 2020, the Medical Radiation Practice Board of Australia made several revisions to its professional capabilities. To address this, medical radiation practitioners, including diagnostic radiographers, are required to escalate urgent ...
Magdalena Dolic, Yaxuan Peng, Keshav Dhingra, Kristal Lee, John McInerney   +4 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Face recognition template in photo indexing : a proposal of hybrid Principal Component Analysis and Triangular Approach (PCAaTA)

, 2016
Many features of human faces play important roles in designing a method that can perform face recognition. There are many current studies in the area of face recognition, but most of them have limitations. The Principal Component Analysis (PCA) is one of
Prasad, P. W. C. (R20735), Al-sadoon, Abeer (R20467), Monem, A., Vu, L. G., Elchouemi, Amr   +4 more
core   +1 more source