Results 81 to 90 of about 2,186,291 (292)

Image interpretation for a multilevel land use classification system [PDF]

The potential use is discussed of three remote sensors for developing a four level land use classification system. Three types of imagery for photointerpretation are presented: ERTS-1 satellite imagery, high altitude photography, and medium altitude ...

core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Classifying pictorial interpretation theories

Prometeica
Analytic philosophy traditionally uses two classification criteria to distinguish theories of pictorial interpretation: mimetic or illusionistic, and natural or non-natural.
Juan Pablo Aguilar Martínez
doaj   +1 more source

Energy considerations for a superlens based on metal/dielectric multilayers

, 2008
We investigate the resolution and absorption losses of a Ag/GaP multilayer superlens. For a fixed source to image distance the resolution is independent of the position of the lens but the losses depend strongly on the lens placement.
Anantha Ramakrishna, Bates, Bennett, Bloemer, Bloemer, Ciraci, de Ceglia, Domenico de Ceglia, D’Aguanno, Ebbesen, Giuseppe D’Aguanno, Liu, Mark J. Bloemer, Michael Scalora, Nadia Mattiucci, Pendry, Podolskiy, Scalora, Scalora, Shin, Shuford   +20 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

A geographical perspective on the Aral Sea crisis: three interpretations of an image

Bulletin of Geography. Socio-Economic Series, 2013
The Aral Sea crisis has gained global notoriety as a human-induced environmental disaster. This paper contextualizes this crisis within a broad geographical framework. Three interpretations of a single photographic image emblematic of the desiccation of
Kristopher D. White
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Mass influx obtained from low-light-level television observations of faint meteors [PDF]

Low light level television systems offer the ability to observe meteors as faint as 10th magnitude which allows the extension of optical meteor data to masses as small as 0.0001 gram.
Clifton, K. S., Naumann, R. J.
core   +1 more source