Results 91 to 100 of about 591,486 (308)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
The image of the heart in poetic and patristic synthesis
RUDN Journal of Studies in Literature and JournalismThe religious, philosophical and poetic context of the functioning of the image of the heart in the discourse of Russian symbolist poets is analyzed. An attempt has been made to discover mythological and Christian (evangelical and patristic) roots in the
Dmitriy M. Bychkov, Kseniya N. Gushchina
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Digital HealthObjectives To map global research on AI-driven histopathological image interpretation in oncology (2000–2024). Methodology Scopus-based bibliometrics using Boolean queries; data exported, cleaned, and analyzed in VOSviewer.
Moutaz W Sweileh
doaj +1 more source
Interpretability-Aware Pruning for Efficient Medical Image Analysis
Accepted at The 1st MICCAI Workshop on Efficient Medical AI ...
Nikita Malik +4 more
openaire +2 more sources
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Multi modal multi-semantic image retrieval
, 2010 PhDThe rapid growth in the volume of visual information, e.g. image, and video can overwhelm users’ ability to find and access the specific visual information of interest to them.
Kesorn, Kraisak
core
Voxel selection in fMRI data analysis based on sparse representation [PDF]
, 2009 Multivariate pattern analysis approaches toward detection of brain regions from fMRI data have been gaining attention recently. In this study, we introduce an iterative sparse-representation-based algorithm for detection of voxels in functional MRI (fMRI)
Namburi, Praneeth +5 more
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source