Results 31 to 40 of about 1,705 (213)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Program-Guided Image Manipulators [PDF]

open access: yes2019 IEEE/CVF International Conference on Computer Vision (ICCV), 2019
Humans are capable of building holistic representations for images at various levels, from local objects, to pairwise relations, to global structures. The interpretation of structures involves reasoning over repetition and symmetry of the objects in the image.
Mao, Jiayuan   +5 more
openaire   +3 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Image Watermarking pada Citra Medis menggunakan Compressive Sensing berbasis Stationary Wavelet Transform

open access: yesJurnal Elkomika, 2020
ABSTRAK Watermarking pada citra medis dilakukan untuk melindungi hak kepemilikan dan keaslian sebuah citra medis. Proses embedding dan extraction dirancang menggunakan metode Stationary Wavelet Transform (SWT) dan Statistical Mean Manipulation (SMM ...
YASQI HAFIZHANA   +3 more
doaj   +1 more source

Proactive Image Manipulation Detection

open access: yes2022 IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR), 2022
Image manipulation detection algorithms are often trained to discriminate between images manipulated with particular Generative Models (GMs) and genuine/real images, yet generalize poorly to images manipulated with GMs unseen in the training. Conventional detection algorithms receive an input image passively.
Vishal Asnani   +4 more
openaire   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

HarmoDehazeDiffusion: Multi-Scale Spatial Fusion Network for Dense Haze Removal

open access: yesApplied Sciences
Image dehazing remains a critical yet challenging task in computer vision. While the existing dehazing methods have achieved notable progress, they still struggle to effectively eliminate dense haze in scenes while maintaining consistent illumination ...
Jiangjie Yu   +3 more
doaj   +1 more source

Effects of image compression on face image manipulation detection: A case study on facial retouching

open access: yesIET Biometrics, 2021
Numerous methods have been introduced to reliably detect digital face image manipulations in the past. Of late, the generalisability of these schemes has been questioned in particular with respect to image post‐processing.
Christian Rathgeb   +3 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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